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IN THIS ISSUE

Journal of the American College of Cardiology

June 18, 2003, Vol. 41, No. 12
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 Articles In this Issue

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Clinical research: clinical trial

Secondary prevention with folic acid: effects on clinical outcomes
Anho Liem, MD; Giny H Reynierse-Buitenwerf; Aeilko H Zwinderman, PhD; J.Wouter Jukema, MD, FACC; Dirk J van Veldhuisen, MD, FACC
J Am Coll Cardiol. 2003;41(12):2105-2113.
doi: 10.1016/S0735-1097(03)00485-6
TOPICS: homocysteine, folic acid, treatment outcome, secondary prevention, creatinine clearance
A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study
Christopher S.R Baker, PhD, MRCP; Andrew Wragg, MRCP; Sanjay Kumar, MRCP; Rodney De Palma; Laurence R.I Baker, MD, FRCP; Charles J Knight, MD, MRCP
J Am Coll Cardiol. 2003;41(12):2114-2118.
doi: 10.1016/S0735-1097(03)00487-X
TOPICS: acetylcysteine, kidney failure, creatinine tests, serum, saline solution
Beraprost therapy for pulmonary arterial hypertension
Robyn J Barst, MD, FACC; Michael McGoon, MD; Vallerie McLaughlin, MD, FACC; Victor Tapson, MD, FCCP; Ronald Oudiz, MD, FACC; Shelley Shapiro, MD; Ivan M Robbins, MD; Richard Channick, MD; David Badesch, MD; Barry K Rayburn, MD, FACC; Robin Flinchbaugh, BS; Jeff Sigman, BA; Carl Arneson, MStat; Roger Jeffs, PhD
J Am Coll Cardiol. 2003;41(12):2119-2125.
doi: 10.1016/S0735-1097(03)00463-7
TOPICS: epoprostenol, hemodynamics, dyspnea, exercise, disease progression, exercise tolerance, world health organization, sodium, ...

Editorial comment

Emerging therapies for pulmonary hypertension: Striving for efficacy and safety*
Peter N Kao, MD, PhD; John L Faul, MD
J Am Coll Cardiol. 2003;41(12):2126-2129.
doi: 10.1016/S0735-1097(03)00468-6
TOPICS: pulmonary hypertension, safety
Circadian variations in acute myocardial infarction: Patients or health care delivery?
Frederick A Spencer, MD, FACC; Richard C Becker, MD
J Am Coll Cardiol. 2003;41(12):2143-2146.
doi: 10.1016/S0735-1097(03)00462-5
TOPICS: myocardial infarction, acute, thrombolytic therapy, angioplasty, delivery of health care
The failing human heart: Another battlefield for the NAD(P)H oxidase?*
Ascan Warnholtz, MD; Thomas Munzel, MD
J Am Coll Cardiol. 2003;41(12):2172-2174.
doi: 10.1016/S0735-1097(03)00472-8
TOPICS: heart, oxidase
The ups and downs of periodic breathing: Implications for mortality in heart failure*
T.Douglas Bradley, MD
J Am Coll Cardiol. 2003;41(12):2182-2184.
doi: 10.1016/S0735-1097(03)00470-4
TOPICS: cheyne-stokes respiration, heart failure, mortality
Genomic medicine and atrial fibrillation*
Luisa Mestroni, MD, FACC, FESC
J Am Coll Cardiol. 2003;41(12):2193-2196.
doi: 10.1016/S0735-1097(03)00459-5
TOPICS: atrial fibrillation
Blockade of atrial angiotensin II type 1 receptors: A novel antiarrhythmic strategy to prevent atrial fibrillation?*
Helmut U Klein, MD; Andreas Goette, MD
J Am Coll Cardiol. 2003;41(12):2205-2206.
doi: 10.1016/S0735-1097(03)00469-8
TOPICS: anti-arrhythmia agents, atrial fibrillation, angiotensin ii, atrium
T-Wave alternans for arrhythmia risk stratification in patients with idiopathic dilated cardiomyopathy*
Richard L Verrier, PhD, FACC; Aneesh V Tolat, MD; Mark E Josephson, MD, FACC
J Am Coll Cardiol. 2003;41(12):2225-2227.
doi: 10.1016/S0735-1097(03)00466-2
TOPICS: cardiac arrhythmia, t-wave alternans, primary idiopathic dilated cardiomyopathy, stratification

Clinical research: myocardial infarction

Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction
Seyyare Beyzade, BSc; Shaoli Zhang, PhD; Yuk-ki Wong, MD, MRCP; Ian N.M Day, MB, PhD, FRCPath; Per Eriksson, PhD; Shu Ye, MD, PhD
J Am Coll Cardiol. 2003;41(12):2130-2137.
doi: 10.1016/S0735-1097(03)00482-0
TOPICS: alleles, myocardial infarction, coronary arteriosclerosis, polymorphism, genes, genotype, metalloproteases, stromelysin 1

Clinical research: interventional cardiology

Outcome of primary angioplasty for acute myocardial infarction during routine duty hours versus during off-hours
Jose P.S Henriques, MD; Arnout P Haasdijk, MD; Felix Zijlstra, MD, PhD
J Am Coll Cardiol. 2003;41(12):2138-2142.
doi: 10.1016/S0735-1097(03)00461-3
TOPICS: myocardial infarction, acute, angioplasty, work schedule
Recombinant nematode anticoagulant protein c2, an inhibitor of the tissue factor/factor VIIa complex, in patients undergoing elective coronary angioplastyAppendix
Arno H.M Moons, MD; Ron J.G Peters, MD, PhD; Nick R Bijsterveld, MD; Jan J Piek, MD, PhD; Martin H Prins, MD, PhD; George P Vlasuk, PhD; William E Rote, PhD; Harry R Büller, MD, PhD
J Am Coll Cardiol. 2003;41(12):2147-2153.
doi: 10.1016/S0735-1097(03)00478-9
TOPICS: anticoagulants, clopidogrel, percutaneous coronary intervention, hemorrhage, caenorhabditis elegans, factor viia, thrombin, thromboplastin ...

Clinical research: heart failure

Growth hormone prolongs survival in experimental postinfarction heart failure
Antonio Cittadini, MD; Jörgen Isgaard, MD; Maria Gaia Monti, PhD; Cosma Casaburi, MD; Angela Di Gianni, MD; Raffaella Serpico, MD; Guido Iaccarino, MD; Luigi Saccà, MD
J Am Coll Cardiol. 2003;41(12):2154-2163.
doi: 10.1016/S0735-1097(03)00483-2
TOPICS: apoptosis, cardiac myocyte, myocardium, heart failure, somatropin, rats, sarcoplasmic reticulum calcium-transporting atpases ...
Increased myocardial NADPH oxidase activity in human heart failure
Christophe Heymes, PhD; Jennifer K Bendall, MSc; Philippe Ratajczak; Alison C Cave, PhD; Jane-Lise Samuel, MD, PhD; Gerd Hasenfuss, MD; Ajay M Shah, MD, FRCP, FAHA
J Am Coll Cardiol. 2003;41(12):2164-2171.
doi: 10.1016/S0735-1097(03)00471-6
TOPICS: myocardium, heart failure, nadph oxidase
Periodic breathing during incremental exercise predicts mortality in patients with chronic heart failure evaluated for cardiac transplantation
Joao J. Leite, MD, PhD; Alfredo J. Mansur, MD, PhD; Humberto F.G. de Freitas, MD; Paulo R. Chizola, MD; Edimar A. Bocchi, MD, PhD; Mario Terra-Filho, MD, PhD; J.Alberto Neder, MD, PhD; Geraldo Lorenzi-Filho, MD, PhD
J Am Coll Cardiol. 2003;41(12):2175-2181.
doi: 10.1016/S0735-1097(03)00460-1
TOPICS: heart failure, chronic, cheyne-stokes respiration, heart transplantation, congestive heart failure, exercise, heart, ...

Clinical research: atrial fibrillation/flutter, tachycardia

Familial atrial fibrillation is a genetically heterogeneous disorder
Dawood Darbar, MD; Kathleen J Herron, BA; Jeffrey D Ballew, MSc; Arshad Jahangir, MD; Bernard J Gersh, MBChB, DPhil, FACC; Win-K Shen, MD, FACC; Stephen C Hammill, MD, FACC; Douglas L Packer, MD, FACC; Timothy M Olson, MD
J Am Coll Cardiol. 2003;41(12):2185-2192.
doi: 10.1016/S0735-1097(03)00465-0
TOPICS: atrial fibrillation, heterogeneity
Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation
Koichiro Kumagai, MD; Hideko Nakashima, MD; Hidenori Urata, MD; Naoki Gondo, MD; Kikuo Arakawa, MD, FACC; Keijiro Saku, MD, FACC
J Am Coll Cardiol. 2003;41(12):2197-2204.
doi: 10.1016/S0735-1097(03)00464-9
TOPICS: atrial fibrillation, atrium, candesartan cilexetil, atrial-based pacing, angiotensin ii type 1 receptor ...
Time course for resolution of left atrial appendage stunning after catheter ablation of chronic atrial flutter
Mitsuaki Takami, MD; Makoto Suzuki, MD; Kaoru Sugi, MD; Takanori Ikeda, MD, FACC
J Am Coll Cardiol. 2003;41(12):2207-2211.
doi: 10.1016/S0735-1097(03)00496-0
TOPICS: anticoagulation, atrial flutter, transesophageal echocardiography, electric countershock, left auricular appendage, cardiac ablation, ...
Focal atrial tachycardia arising from the mitral annulus: Electrocardiographic and electrophysiologic characterization
Peter M Kistler, MBBS; Prashanthan Sanders, MBBS; Azlan Hussin, MBBS; Joseph B Morton, MBBS; Jitendra K Vohra, MD; Paul B Sparks, MBBS, PhD; Jonathan M Kalman, MBBS, PhD, FACC
J Am Coll Cardiol. 2003;41(12):2212-2219.
doi: 10.1016/S0735-1097(03)00484-4
TOPICS: electrocardiogram, tachycardia, atrial tachycardia, p wave feature, endocardium, atrium, catheter device, ablation, ...

Clinical research: ventricular tachycardia

Usefulness of microvolt T-wave alternans for prediction of ventricular tachyarrhythmic events in patients with dilated cardiomyopathy: results from a prospective observational study
Stefan H Hohnloser, MD, FACC; Thomas Klingenheben, MD; Daniel Bloomfield, MD; Omar Dabbous, MD, MPH; Richard J Cohen, MD, PhD
J Am Coll Cardiol. 2003;41(12):2220-2224.
doi: 10.1016/S0735-1097(03)00467-4
TOPICS: cardiomyopathy, dilated, t-wave alternans, heart ventricle, stratification, microvolt t-wave alternans
Short-term results of substrate mapping and radiofrequency ablation of ischemic ventricular tachycardia using a saline-irrigated catheter
Vivek Y Reddy, MD, FACC; Petr Neuzil, MD; Milos Taborsky, MD; Jeremy N Ruskin, MD, FACC
J Am Coll Cardiol. 2003;41(12):2228-2236.
doi: 10.1016/S0735-1097(03)00492-3
TOPICS: ischemic ventricular tachycardia, cardiac ablation, catheter device, radiofrequency ablation, ablation, saline solution ...

Clinical research: pulmonary vascular disorders

Primary pulmonary hypertension may be a heterogeneous disease with a second locus on chromosome 2q31
Matthias Rindermann; Ekkehard Grünig, MD; Albrecht von Hippel; Rolf Koehler, PhD; Gabriel Miltenberger-Miltenyi, MD, PhD; Derliz Mereles, MD; Karlin Arnold; Michael Pauciulo; William Nichols, PhD; Horst Olschewski, MD; Marius M Hoeper, MD; Jörg Winkler, MD; Hugo A Katus, MD; Wolfgang Kübler, MD, FRCP; Claus R Bartram, MD; Bart Janssen, PhD
J Am Coll Cardiol. 2003;41(12):2237-2244.
doi: 10.1016/S0735-1097(03)00491-1
TOPICS: primary pulmonary hypertension, mutation, exercise, heterogeneity, chromosomes, bone morphogenetic protein receptor, type ...
Right heart thrombi in pulmonary embolism: Results from the international cooperative pulmonary embolism registry
Adam Torbicki, MD; Nazzareno Galié, MD; Anna Covezzoli, BS; Elisa Rossi, BS; Marisa De Rosa, PhD; Samuel Z Goldhaber, MD
J Am Coll Cardiol. 2003;41(12):2245-2251.
doi: 10.1016/S0735-1097(03)00479-0
TOPICS: heparin, pulmonary embolism, echocardiography, thrombus, right side of heart
Prevalence of “silent” pulmonary emboli in adults after the Fontan operation
Chetan Varma, MBBS, MD; Matthew R Warr, BSc; Aaron L Hendler, MD; Narinder S Paul, MD; Gary D Webb, MD, FACC; Judith Therrien, MD
J Am Coll Cardiol. 2003;41(12):2252-2258.
doi: 10.1016/S0735-1097(03)00490-X
TOPICS: pulmonary embolism, fontan procedure, thrombus

Clinical research: congenital heart disease

Ambulatory blood pressure, left ventricular mass, and conduit artery function late after successful repair of coarctation of the aorta
Marcello de Divitiis, MD; Carlo Pilla, MD; Mia Kattenhorn, BSc; Ann Donald, AVT; Mariutzka Zadinello, MD; Sharon Wallace, BA; Andrew Redington, FRCP; John Deanfield, FRCP
J Am Coll Cardiol. 2003;41(12):2259-2265.
doi: 10.1016/S0735-1097(03)00480-7
TOPICS: aortic coarctation, echocardiography, conduit implant, systolic blood pressure, blood pressure, dilatation, pathologic, ...
Intramyocardial synthesis of pro- and anti-inflammatory cytokines in infants with congenital cardiac defects
Ma Qing, MD; Kathrin Schumacher, MD; Ruth Heise; Michael Wöltje, PhD; Jaime F Vazquez-Jimenez, MD; Thomas Richter, MD; Monika Arranda-Carrero, MD; John Hess, MD; Götz von Bernuth, MD; Marie-Christine Seghaye, MD
J Am Coll Cardiol. 2003;41(12):2266-2274.
doi: 10.1016/S0735-1097(03)00477-7
TOPICS: anti-inflammatory agents, cytokine, myocardium, western blotting, congenital heart defect, ventricular septal defect, ...

Clinical research: cardiac findings in Cushing's syndrome

Left ventricular structural and functional characteristics in Cushing’s syndrome
Maria Lorenza Muiesan, MD; Mario Lupia, MD; Massimo Salvetti, MD; Consuelo Grigoletto, MD; Nicoletta Sonino, MD; Marco Boscaro, MD; Enrico Agabiti Rosei, MD; Franco Mantero, MD; Francesco Fallo, MD
J Am Coll Cardiol. 2003;41(12):2275-2279.
doi: 10.1016/S0735-1097(03)00493-5
TOPICS: cushing syndrome, diastole, heart ventricle

Clinical research: mitral regurgitation

Plasma natriuretic peptide levels increase with symptoms and severity of mitral regurgitation
Timothy M Sutton, MB, ChB; Ralph A.H Stewart, MD; Ivor L Gerber, MB, ChB; Teena M West, MSc; A.Mark Richards, MD, DSc; Timothy G Yandle, PhD; Andrew J Kerr, MB, ChB
J Am Coll Cardiol. 2003;41(12):2280-2287.
doi: 10.1016/S0735-1097(03)00486-8
TOPICS: mitral valve insufficiency, brain natriuretic peptide, plasma, natriuretic peptides

Basic science

High-density lipoprotein increases the abundance of eNOS protein in human vascular endothelial cells by increasing its half-life
Maria E Rämet, MD; Mika Rämet, MD, PhD; Qing Lu, MD, PhD; Moriah Nickerson, BS; Markku J Savolainen, MD, PhD; Amy Malzone, BS; Richard H Karas, MD, PhD, FACC
J Am Coll Cardiol. 2003;41(12):2288-2297.
doi: 10.1016/S0735-1097(03)00481-9
TOPICS: half-life, endothelial cells, high density lipoproteins, nitric oxide synthase, apolipoprotein a-i, proto-oncogene ...

Letter to the editor

Reply
Mehrdad Saririan, MD; Mark Eisenberg, MD, MPH, FACC
J Am Coll Cardiol. 2003;41(12):2298-2299.
doi: 10.1016/S0735-1097(03)00489-3
TOPICS: #
The art and science of transmyocardial laser revascularization
Keith A Horvath, MD
J Am Coll Cardiol. 2003;41(12):2298-2298.
doi: 10.1016/S0735-1097(03)00495-9
TOPICS: #
Mitochondrial dysfunction in heart failure
Jose Marin-Garcia, MD
J Am Coll Cardiol. 2003;41(12):2299-2299.
doi: 10.1016/S0735-1097(03)00494-7
TOPICS: #
Reply
Robert J Scheubel, MD
J Am Coll Cardiol. 2003;41(12):2299-2299.
doi: 10.1016/S0735-1097(03)00488-1
TOPICS: #
Hyperglycemia and no-reflow phenomenon in acute myocardial infarction
Felix Zijlstra, MD, PhD, FACC; Iwan C.C van der Horst, MD; Arnoud W.J van’t Hof, MD, PhD; Henk J.G Bilo, MD, PhD
J Am Coll Cardiol. 2003;41(12):2300-2300.
doi: 10.1016/S0735-1097(03)00474-1
TOPICS: #
Reply
Katsuomi Iwakura, MD
J Am Coll Cardiol. 2003;41(12):2300-2300.
doi: 10.1016/S0735-1097(03)00473-X
TOPICS: #

Articles

Author Index
J Am Coll Cardiol. 2003;41(12):2301-2306.
doi: 10.1016/S0735-1097(03)00569-2
TOPICS: #
Subject Index
J Am Coll Cardiol. 2003;41(12):2307-2328.
doi: 10.1016/S0735-1097(03)00570-9
TOPICS: #
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