ON THE COVER Axial midventricular CT and Rb-82 PET fused image showing substantial misregistration. (Panel A) The misregistration causes an apparent anterolateral wall defect (Panel B) which disappears after manual realignment (Panel C). Images provided by Paolo Raggi, MD, FACC, and Jonathan Nye, PhD, Department of Medicine and Radiology, Emory University School of Medicine, Atlanta, GA