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Legend. To prevent post-MI cardiac remodeling, a biodegradable cardiac patch (P) was applied to subacute infarcts in a rat model (below, black arrows) and compared to controls (above). Eight weeks after patch implantation, increased myocardial wall thickness (middle, white arrow) was seen and histology revealed contractile smooth muscle bundles (right, black arrows). See pages 2294 and 2296.