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Cover Figure


Legend. Anatomic distribution of focal atrial tachycardias. In the lead V1, a negative or +/- P-wave was 100% specific for RA and a + or -/+ P-wave showed a sensitivity of 100% for an LA focus. See pages 1013 and 1014.

Legend. 3D isochronal maps of RA (top) and RV (bottom) during sinus rhythm before (left) and after (right) carbenoxolone. RA and RV activation (red) initiate from sinus node (red) and RV apex, respectively, and propagates as (blue) wavefront. Carbenoxolone, an anti-peptic ulcer drug, reduces wavefront propagation velocity through gap junction uncoupling and without affecting cellular ionic channels and refractoriness. See page 1244.

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