State-of-the-Art Paper:

Martial G. Bourassa, Ady Butnaru, Jacques Lespérance, and Jean-Claude Tardif

Symptomatic myocardial bridges: overview of ischemic mechanisms and current diagnostic and treatment strategies
J Am Coll Cardiol 2003 41: 351-359. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical study: acute coronary syndrome:

Sotirios Tsimikas, Claes Bergmark, Reinaldo W. Beyer, Raj Patel, Jennifer Pattison, Elizabeth Miller, Joseph Juliano, and Joseph L. Witztum

Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes
J Am Coll Cardiol 2003 41: 360-370. [Abstract] [Full Text] [Figures Only] [PDF]  

Padma Kaul, L. Kristin Newby, Yuling Fu, Vic Hasselblad, Kenneth W. Mahaffey, Robert H. Christenson, Robert A. Harrington, E. Magnus Ohman, Eric J. Topol, Robert M. Califf, Frans Van de Werf, Paul W. Armstrong the PARAGON-B Investigators

Troponin T and quantitative ST-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients
J Am Coll Cardiol 2003 41: 371-380. [Abstract] [Full Text] [Figures Only] [PDF]  

Umesh N. Khot, Micky Mishra, M. Hilal Yamani, Nicholas G. Smedira, Emil Paganini, Mike Yeager, Tiffany Buda, Patrick M. McCarthy, James B. Young, and Randall C. Starling

Severe renal dysfunction complicating cardiogenic shock is not a contraindication to mechanical support as a bridge to cardiac transplantation
J Am Coll Cardiol 2003 41: 381-385. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical study: interventional cardiology:

Thaddeus R. Tolleson, J. Conor O’Shea, John A. Bittl, William B. Hillegass, Kathryn A. Williams, Glenn Levine, Robert A. Harrington, and James E. Tcheng

Relationship between heparin anticoagulation and clinical outcomes in coronary stent intervention: observations from the ESPRIT trial
J Am Coll Cardiol 2003 41: 386-393. [Abstract] [Full Text] [Figures Only] [PDF]  

Jonathan D. Marmur, Sunil X. Anand, Ramanjit S. Bagga, Jawed Fareed, Chi-Miau Pan, Samin K. Sharma, and Merwin F. Richard

The activated clotting time can be used to monitor the low molecular weight heparin dalteparin after intravenous administration
J Am Coll Cardiol 2003 41: 394-402. [Abstract] [Full Text] [Figures Only] [PDF]  

Christodoulos Stefanadis, Konstantinos Toutouzas, Eleftherios Tsiamis, Ioannis Mitropoulos, Costas Tsioufis, Ioannis Kallikazaros, Christos Pitsavos, and Pavlos Toutouzas

Thermal heterogeneity in stable human coronary atherosclerotic plaques is underestimated in vivo: the "cooling effect" of blood flow
J Am Coll Cardiol 2003 41: 403-408. [Abstract] [Full Text] [Figures Only] [PDF]  

Robert Bonvini, Iris Baumgartner, Do Dai Do, Mario Alerci, Jeanne-Marie Segatto, Paolo Tutta, Kurt Jäger, Markus Aschwanden, Ernst Schneider, Beatrice Amann-Vesti, Richard Greiner, Felix Mahler, and Augusto Gallino

Late acute thrombotic occlusion after endovascular brachytherapy and stenting of femoropopliteal arteries
J Am Coll Cardiol 2003 41: 409-412. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical study: atherosclerosis:

C. Noel Bairey Merz, B. Delia Johnson, Barry L. Sharaf, Vera Bittner, Sarah L. Berga, Glenn D. Braunstein, T. Keta Hodgson, Karen A. Matthews, Carl J. Pepine, Steven E. Reis, Nathaniel Reichek, William J. Rogers, Gerald M. Pohost, Sheryl F. Kelsey, George Sopko WISE Study Group

Hypoestrogenemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE study
J Am Coll Cardiol 2003 41: 413-419. [Abstract] [Full Text] [Figures Only] [PDF]  

Todd J. Anderson, Jaroslav Hubacek, D. George Wyse, and Merril L. Knudtson

Effect of chelation therapy on endothelial function in patients with coronary artery disease: PATCH substudy
J Am Coll Cardiol 2003 41: 420-425. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical study: heart failure/cardiac transplantation:

Randy W. Braith, Roger M. Mills, Christopher S. Wilcox, Gary L. Davis, James A. Hill, and Charles E. Wood

High-dose angiotensin-converting enzyme inhibition restores body fluid homeostasis in heart-transplant recipients
J Am Coll Cardiol 2003 41: 426-432. [Abstract] [Full Text] [Figures Only] [PDF]  

Editorial Comments:

Howard J. Eisen

Hypertension in heart transplant recipients: more than just cyclosporine
J Am Coll Cardiol 2003 41: 433-434. [Full Text] [PDF]  

Clinical study: cardiac ultrasound:

Damien Garcia, Jean G. Dumesnil, Louis-Gilles Durand, Lyes Kadem, and Philippe Pibarot

Discrepancies between catheter and Doppler estimates of valve effective orifice area can be predicted from the pressure recovery phenomenon: practical implications with regard to quantification of aortic stenosis severity
J Am Coll Cardiol 2003 41: 435-442. [Abstract] [Full Text] [Figures Only] [PDF]  

Editorial Comments:

Robert A. Levine and Ehud Schwammenthal

Stenosis is in the eye of the observer: impact of pressure recovery on assessing aortic valve area
J Am Coll Cardiol 2003 41: 443-445. [Full Text] [PDF]  

Clinical study: arrhythmias:

Sohail A. Hassan, Hakan Oral, Christoph Scharf, Aman Chugh, Frank Pelosi, Bradley P. Knight, S. Adam Strickberger, and Fred Morady

Rate-dependent effect of verapamil on atrial refractoriness
J Am Coll Cardiol 2003 41: 446-451. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical study: radionuclide imaging:

Daniel B. Fram, Rabih R. Azar, Alan W. Ahlberg, Linda D. Gillam, Joseph F. Mitchel, Francis J. Kiernan, Jeffrey A. Hirst, Jeffrey F. Mather, Edward Ficaro, Gizelle Cyr, David Waters, and Gary V. Heller

Duration of abnormal SPECT myocardial perfusion imaging following resolution of acute ischemia: an angioplasty model
J Am Coll Cardiol 2003 41: 452-459. [Abstract] [Full Text] [Figures Only] [PDF]  

Kira Q. Stolen, Jukka Kemppainen, Heikki Ukkonen, Kari K. Kalliokoski, Matti Luotolahti, Pertti Lehikoinen, Helena Hämäläinen, Tiina Salo, K. E. Juhani Airaksinen, Pirjo Nuutila, and Juhani Knuuti

Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopathy
J Am Coll Cardiol 2003 41: 460-467. [Abstract] [Full Text] [Figures Only] [PDF]  

Editorial Comments:

Robert J. Gropler

Noninvasive measurements of myocardial oxygen consumption—can we do better?
J Am Coll Cardiol 2003 41: 468-470. [Full Text] [PDF]  

Clinical study: wine, nicotine, and cardiovascular disease:

Thomas Wallerath, Daniela Poleo, Huige Li, and Ulrich Förstermann

Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects
J Am Coll Cardiol 2003 41: 471-478. [Abstract] [Full Text] [Figures Only] [PDF]  

Editorial Comments:

Robert A. Vogel

Vintners and vasodilators: are French red wines more cardioprotective?
J Am Coll Cardiol 2003 41: 479-481. [Full Text] [PDF]  

Clinical study: wine, nicotine, and cardiovascular disease:

Jun Suzuki, Evelyn Bayna, Erminia Dalle Molle, and Wilbur Y. W. Lew

Nicotine inhibits cardiac apoptosis induced by lipopolysaccharide in rats
J Am Coll Cardiol 2003 41: 482-488. [Abstract] [Full Text] [Figures Only] [PDF]  

Christopher Heeschen, Michael Weis, and John P. Cooke

Nicotine promotes arteriogenesis
J Am Coll Cardiol 2003 41: 489-496. [Abstract] [Full Text] [Figures Only] [PDF]  

Editorial Comments:

Neal L. Benowitz

Basic cardiovascular research and its implications for the medicinal use of nicotine
J Am Coll Cardiol 2003 41: 497-498. [Full Text] [PDF]  

Experimental Studies:

Luciano Cominacini, Anna Fratta Pasini, Ulisse Garbin, Antonio Pastorino, Anna Rigoni, Cristina Nava, Anna Davoli, Vincenzo Lo Cascio, and Tatsuya Sawamura

The platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells
J Am Coll Cardiol 2003 41: 499-507. [Abstract] [Full Text] [Figures Only] [PDF]  

Robert M. Bell and Derek M. Yellon

Atorvastatin, administered at the onset of reperfusion, and independent oflipid lowering, protects the myocardiumby up-regulating a pro-survival pathway
J Am Coll Cardiol 2003 41: 508-515. [Abstract] [Full Text] [Figures Only] [PDF]  

Editor's Page:

Anthony N. DeMaria

Duplicate publication: insights into the essence of a medical journal
J Am Coll Cardiol 2003 41: 516-517. [Full Text] [PDF]  

Letters to the Editor:

Cindy L. Grines

Reply
J Am Coll Cardiol 2003 41: 518-519. [Full Text] [PDF]  

Barry Silverman

Safety and benefits of transferring patients with acute myocardial infarction to interventional center for immediate angioplasty
J Am Coll Cardiol 2003 41: 518. [Full Text] [PDF]  

Christoph Pechlaner and Romuald Bellmann

Patients with high-risk acute myocardial infarction randomized to one of two treatment strategies: delay and eligibility questions
J Am Coll Cardiol 2003 41: 518. [Full Text] [PDF]  

Philip D. Hansten

Possible risks to patients receiving statins combined with other medications
J Am Coll Cardiol 2003 41: 519-520. [Full Text] [PDF]  

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