Editorial:

Editorial
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Myocardial Infarction:

Karl-Ludwig Neuhaus, G. Peter Molhoek, Uwe Zeymer, Ulrich Tebbe, Karl Wegscheider, Rolf Schröder, Anne Camez, G. Jan Laarman, Gilles M. Grollier, Dirk J. A. Lok, Holger Kuckuck, Peter Lazarus for the HIT-4 Investigators

Recombinant hirudin (lepirudin) for the improvement of thrombolysis with streptokinase in patients with acute myocardial infarction: Results of the HIT-4 trial
J Am Coll Cardiol 1999 34: 966-973. [Abstract] [Full Text] [Figures Only] [PDF]  

C. Michael Gibson, Kathryn A. Ryan, Sabina A. Murphy, Rebecca Mesley, Susan J. Marble, Robert P. Giugliano, Christopher P. Cannon, Elliott M. Antman, Eugene Braunwald for the TIMI Study Group

Impaired coronary blood flow in nonculprit arteries in the setting of acute myocardial infarction
J Am Coll Cardiol 1999 34: 974-982. [Abstract] [Full Text] [Figures Only] [PDF]  

Hirofumi Soejima, Hisao Ogawa, Hirofumi Yasue, Koichi Kaikita, Keiji Takazoe, Koichi Nishiyama, Kenji Misumi, Shinzo Miyamoto, Michihiro Yoshimura, Kiyotaka Kugiyama, Shin Nakamura, and Ichiro Tsuji

Angiotensin-converting enzyme inhibition reduces monocyte chemoattractant protein-1 and tissue factor levels in patients with myocardial infarction
J Am Coll Cardiol 1999 34: 983-988. [Abstract] [Full Text] [Figures Only] [PDF]  

Myocardial Ischemia:

Etienne P. Hoffer, Walthère Dewé, Carmine Celentano, and Luc A. Piérard

Low-level exercise echocardiography detects contractile reserve and predicts reversible dysfunction after acute myocardial infarction: Comparison with low-dose dobutamine echocardiography
J Am Coll Cardiol 1999 34: 989-997. [Abstract] [Full Text] [Figures Only] [PDF]  

Kuo-Chun Hung, Fun-Chung Lin, Ming-Shyan Chern, Hern-Jia Chang, I.-Chang Hsieh, and Delon Wu

Mechanisms and clinical significance of transient atrioventricular block during dobutamine stress echocardiography
J Am Coll Cardiol 1999 34: 998-1004. [Abstract] [Full Text] [Figures Only] [PDF]  

Christian A. Schneider, Eberhard Voth, Detlef Moka, Frank M. Baer, Jacques Melin, Anne Bol, Rainer Wagner, Harald Schicha, Erland Erdmann, and Udo Sechtem

Improvement of myocardial blood flow to ischemic regions by angiotensin- converting enzyme inhibition with quinaprilat IV: A study using [¹⁵O] water dobutamine stress positron emission tomography
J Am Coll Cardiol 1999 34: 1005-1011. [Abstract] [Full Text] [Figures Only] [PDF]  

Jean-Luc Monin, J.érôme Garot, Marielle Scherrer-Crosbie, Jean Rosso, Anne-Marie Duval-Moulin, Patrick Dupouy, Emmanuel Teiger, Alain Castaigne, Jean-Claude Cachin, Jean-Luc Dubois-Rande, and Pascal Gueret

Prediction of functional recovery of viable myocardium after delayed revascularization in postinfarction patients: Accuracy of dobutamine stress echocardiography and influence of long-term vessel patency
J Am Coll Cardiol 1999 34: 1012-1019. [Abstract] [Full Text] [Figures Only] [PDF]  

Acute Coronary Syndromes:

Richard C. Becker, Frederick A. Spencer, Youfu Li, Steven P. Ball, Yunsheng Ma, Thomas Hurley, and James Hebert

Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes: Potential mechanisms for heightened prothrombotic potential
J Am Coll Cardiol 1999 34: 1020-1027. [Abstract] [Full Text] [Figures Only] [PDF]  

Interventional Cardiology:

Takahiko Suzuki, Hiroaki Hosokawa, Osamu Katoh, Tamotsu Fujita, Katsumi Ueno, Shinichi Takase, Kenshi Fujii, Hideo Tamai, Tadanori Aizawa, Tetsu Yamaguchi, Hiroyuki Kurogane, Mikihiro Kijima, Hirotaka Oda, Etsuo Tsuchikane, Tomoaki Hinohara, Peter J. Fitzgerald for the ABACAS Investigators

Effects of adjunctive balloon angioplasty after intravascular ultrasound-guided optimal directional coronary atherectomy: The result of adjunctive balloon angioplasty after coronary atherectomy study (ABACAS)
J Am Coll Cardiol 1999 34: 1028-1035. [Abstract] [Full Text] [Figures Only] [PDF]  

Istvan Kosa, Rudolf Blasini, Jan Schneider-Eicke, Timm Dickfeld, Franz J. Neumann, Sibylle Ziegler, Ichiro Matsunari, Jodi Neverve, Albert Schömig, and Markus Schwaiger

Early recovery of coronary flow reserve after stent implantation as assessed by positron emission tomography
J Am Coll Cardiol 1999 34: 1036-1041. [Abstract] [Full Text] [Figures Only] [PDF]  

Etsuo Tsuchikane, Satoru Sumitsuji, Nobuhisa Awata, Toshinori Nakamura, Tomoko Kobayashi, Masahiro Izumi, Satoru Otsuji, Hitone Tateyama, Makoto Sakurai, and Tohru Kobayashi

Final results of the STent versus directional coronary Atherectomy Randomized Trial (START)
J Am Coll Cardiol 1999 34: 1050-1057. [Abstract] [Full Text] [Figures Only] [PDF]  

William S. Weintraub, Steven Culler, Stephen J. Boccuzzi, John R. Cook, Andrzej S. Kosinski, David J. Cohen, Joy Burnette for the RESTORE Trial Study Group

Economic impact of GPIIB/IIIA blockade after high-risk angioplasty: Results from the restore trial
J Am Coll Cardiol 1999 34: 1061-1066. [Abstract] [Full Text] [Figures Only] [PDF]  

Patrick W. Serruys, I. Patrick Kay, Clemens Disco, Niteen V. Deshpande, Pim J. de Feyter on behalf of the BENESTENT I BENESTENT II Pilot BENESTENT II and MUSIC Study Groups

Periprocedural quantitative coronary angiography after Palmaz-Schatz stent implantation predicts the restenosis rate at six months: Results of a meta-analysis of the belgian netherlands stent study (BENESTENT) I, BENESTENT II pilot, BENESTENT II and MUSIC trials
J Am Coll Cardiol 1999 34: 1067-1074. [Abstract] [Full Text] [Figures Only] [PDF]  

Pedro R. Moreno, John T. Fallon, Alvaro M. Murcia, Miltiadis N. Leon, Hector Simosa, Valentín Fuster, and Igor F. Palacios

Tissue characteristics of restenosis after percutaneous transluminal coronary angioplasty in diabetic patients
J Am Coll Cardiol 1999 34: 1045-1049. [Abstract] [Full Text] [PDF]  

Coronary Artery Disease:

Manolis Vavuranakis, Christodoulos Stefanadis, Eleni Triandaphyllidi, Konstantinos Toutouzas, and Pavlos Toutouzas

Coronary artery distensibility in diabetic patients with simultaneous measurements of luminal area and intracoronary pressure: Evidence of impaired reactivity to nitroglycerin
J Am Coll Cardiol 1999 34: 1075-1081. [Abstract] [Full Text] [Figures Only] [PDF]  

Implantable Defibrillators:

Suneet Mittal, Sei Iwai, Kenneth M. Stein, Steven M. Markowitz, David J. Slotwiner, and Bruce B. Lerman

Long-term outcome of patients with unexplained syncope treated with an electrophysiologic-guided approach in the implantable cardioverter-defibrillator era
J Am Coll Cardiol 1999 34: 1082-1089. [Abstract] [Full Text] [Figures Only] [PDF]  

Michael J. Domanski, Sanjeev Sakseena, Andrew E. Epstein, Alfred P. Hallstrom, Michael A. Brodsky, Soo Kim, Scott Lancaster, Eleanor Schron for the AVID Investigators

Relative effectiveness of the implantable cardioverter-defibrillator and antiarrhythmic drugs in patients with varying degrees of left ventricular dysfunction who have survived malignant ventricular arrhythmias
J Am Coll Cardiol 1999 34: 1090-1095. [Abstract] [Full Text] [Figures Only] [PDF]  

Electrophysiology:

Antonis S. Manolis, Vassilis Vassilikos, Themos Maounis, Helen Melita-Manolis, Lefteris Psarros, Alex Haliasos, and Dennis V. Cokkinos

Detection of myocardial injury during radiofrequency catheter ablation by measuring serum cardiac troponin I levels: procedural correlates
J Am Coll Cardiol 1999 34: 1099-1105. [Abstract] [Full Text] [Figures Only] [PDF]  

Laszlo Littmann

Large T wave inversion and QT prolongation associated with pulmonary edema: A report of nine cases
J Am Coll Cardiol 1999 34: 1106-1110. [Abstract] [Full Text] [Figures Only] [PDF]  

Andrew E. Epstein, Judy Powell, Qing Yao, Celeste Ocampo, Scott Lancaster, Yves Rosenberg, David S. Cannom, John M. Herre, H. Leon Greene the AVID Investigators

In-hospital versus out-of-hospital presentation of life-threatening ventricular arrhythmias predicts survival: Results from the AVID registry
J Am Coll Cardiol 1999 34: 1111-1116. [Abstract] [Full Text] [Figures Only] [PDF]  

Hypertrophic Cardiomyopathy:

Michael Y. Henein, Christine A. O’Sullivan, Ihab S. Ramzy, Ulrich Sigwart, and Derek G. Gibson

Electromechanical left ventricular behavior after nonsurgical septal reduction in patients with hypertrophic obstructive cardiomyopathy
J Am Coll Cardiol 1999 34: 1117-1122. [Abstract] [Full Text] [Figures Only] [PDF]  

Sherif F. Nagueh, Nasser M. Lakkis, Katherine J. Middleton, Donna Killip, William A. Zoghbi, Miguel A. Quiñones, and William H. Spencer III

Changes in left ventricular filling and left atrial function six months after nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy
J Am Coll Cardiol 1999 34: 1123-1128. [Abstract] [Full Text] [Figures Only] [PDF]  

Valve Disease:

Maurice Enriquez-Sarano, William K. Freeman, Christophe M. Tribouilloy, Thomas A. Orszulak, Bijoy K. Khandheria, James B. Seward, Kent R. Bailey, and A. Jamil Tajik

Functional anatomy of mitral regurgitation: Accuracy and outcome implications of transesophageal echocardiography
J Am Coll Cardiol 1999 34: 1129-1136. [Abstract] [Full Text] [Figures Only] [PDF]  

Maurice Enriquez-Sarano, Arsene-Joseph Basmadjian, Andrea Rossi, Kent R. Bailey, James B. Seward, and A. Jamil Tajik

Progression of mitral regurgitation: A prospective Doppler echocardiographic study
J Am Coll Cardiol 1999 34: 1137-1144. [Abstract] [Full Text] [Figures Only] [PDF]  

Miltiadis N. Leon, Lari C. Harrell, Hector F. Simosa, Nasser A. Mahdi, Asad Pathan, Julio Lopez-Cuellar, Ignacio Inglessis, Pedro R. Moreno, and Igor F. Palacios

Mitral balloon valvotomy for patients with mitral stenosis in atrial fibrillation: Immediate and long-term results
J Am Coll Cardiol 1999 34: 1145-1152. [Abstract] [Full Text] [Figures Only] [PDF]  

Andrew J. Burger, Howard B. Sherman, Mark J. Charlamb, Juhee Kim, Laura A. Asinas, Stacy R. Flickner, and George L. Blackburn

Low prevalence of valvular heart disease in 226 phentermine-fenfluramine protocol subjects prospectively followed for up to 30 months
J Am Coll Cardiol 1999 34: 1153-1158. [Abstract] [Full Text] [PDF]  

Bypass Surgery:

Verghese Mathew, Diane E. Grill, Christopher G. Scott, J. Aaron Grantham, Henry H. Ting, Kirk N. Garratt, and David R. Holmes Jr.

The influence of abciximab use on clinical outcome after aortocoronary vein graft interventions
J Am Coll Cardiol 1999 34: 1163-1169. [Abstract] [Full Text] [Figures Only] [PDF]  

Heart Failure:

Randy W. Braith, Michael A. Welsch, Matthew S. Feigenbaum, Heidi A. Kluess, and Carl J. Pepine

Neuroendocrine activation in heart failure is modified by endurance exercise training
J Am Coll Cardiol 1999 34: 1170-1175. [Abstract] [Full Text] [Figures Only] [PDF]  

Geriatric Cardiology:

Bastiaan T. Heijmans, Rudi G. J. Westendorp, Dick L. Knook, Cornelis Kluft, and P. Eline Slagboom

Angiotensin I–converting enzyme and plasminogen activator inhibitor-1 gene variants: risk of mortality and fatal cardiovascular disease in an elderly population-based cohort
J Am Coll Cardiol 1999 34: 1176-1183. [Abstract] [Full Text] [Figures Only] [PDF]  

Pulmonary Hypertension:

Stuart Rich and Vallerie V. McLaughlin

The effects of chronic prostacyclin therapy on cardiac output and symptoms in primary pulmonary hypertension
J Am Coll Cardiol 1999 34: 1184-1187. [Abstract] [Full Text] [Figures Only] [PDF]  

Noritoshi Nagaya, Masaaki Uematsu, Yoshiaki Okano, Toru Satoh, Shingo Kyotani, Fumio Sakamaki, Norifumi Nakanishi, Kunio Miyatake, and Takeyoshi Kunieda

Effect of orally active prostacyclin analogue on survival of outpatients with primary pulmonary hypertension
J Am Coll Cardiol 1999 34: 1188-1192. [Abstract] [Full Text] [Figures Only] [PDF]  

New Methods:

Carlo Caiati, Cristiana Montaldo, Norma Zedda, Roberta Montisci, Massimo Ruscazio, Giorgio Lai, Mauro Cadeddu, Luigi Meloni, and Sabino Iliceto

Validation of a new noninvasive method (contrast-enhanced transthoracic second harmonic echo Doppler) for the evaluation of coronary flow reserve: Comparison with intracoronary Doppler flow wire
J Am Coll Cardiol 1999 34: 1193-1200. [Abstract] [Full Text] [Figures Only] [PDF]  

Endothelial Function:

Josef Niebauer, J.ózef Dulak, Jason R. Chan, Philip S. Tsao, and John P. Cooke

Gene transfer of nitric oxide synthase: Effects on endothelial biology
J Am Coll Cardiol 1999 34: 1201-1207. [Abstract] [Full Text] [Figures Only] [PDF]  

Experimental Studies:

Tom Saldeen, Dayuan Li, and Jawahar L. Mehta

Differential effects of - and -tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis
J Am Coll Cardiol 1999 34: 1208-1215. [Abstract] [Full Text] [Figures Only] [PDF]  

Daniël De Wolf, Luc Foubert, Yves Van Belleghem, Kathy Mareels, Dirk Matthys, Henri Verhaaren, and Guido Van Nooten

The influence of low afterload on the nature of the stress-velocity relationship
J Am Coll Cardiol 1999 34: 1219-1225. [Abstract] [Full Text] [Figures Only] [PDF]  

ACC/AHA Guidelines for CABG Surgeries:

Kim A. Eagle, Robert A. Guyton, Ravin Davidoff, Gordon A. Ewy, James Fonger, Timothy J. Gardner, John Parker Gott, Howard C. Herrmann, Robert A. Marlow, William C. Nugent, Gerald T. O’Connor, Thomas A. Orszulak, Richard E. Rieselbach, William L. Winters, Salim Yusuf, Raymond J. Gibbons, Joseph S. Alpert, Kim A. Eagle, Timothy J. Gardner, Arthur Garson Jr., Gabriel Gregoratos, Richard O. Russell, and Sidney C. Smith Jr.

ACC/AHA guidelines for coronary artery bypass graft surgery: A report of the American College of Cardiology/ American Heart Association task force on Practice Guidelines (Committee to revise the 1991 Guidelines for Coronary Artery Bypass Graft Surgery)
J Am Coll Cardiol 1999 34: 1262-1347. [Full Text] [Figures Only] [PDF]  

AHA/ACC Scientific Statement:

Scott M. Grundy, Richard Pasternak, Philip Greenland, Sidney Smith Jr, and Valentin Fuster

Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology
J Am Coll Cardiol 1999 34: 1348-1359. [Full Text] [Figures Only] [PDF]  

Call to Action:

Daniel Levy, C. Noel Bairey Merz, Robert J. Cody, Fetnat M. Fouad-Tarazi, Charles K. Francis, Marc A. Pfeffer, Neal A. Scott, H. J. C. Swan, Malcolm P. Taylor, and Myron H. Weinberger

Hypertension detection, treatment and control: A call to action for cardiovascular specialists
J Am Coll Cardiol 1999 34: 1360-1362. [Full Text] [PDF]  

Erratum:

Corrections
J Am Coll Cardiol 1999 34: 1363. [Full Text] [Figures Only] [PDF]  

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