CLINICAL RESEARCH: TRANSIENT APICAL BALLOONING
Four-Year Recurrence Rate and Prognosis of the Apical Ballooning Syndrome
Ahmad A. Elesber, MD*,
Abhiram Prasad, MD, FACC*,
Ryan J. Lennon, MS ,
R. Scott Wright, MD, FACC, FESC*,
Amir Lerman, MD, FACC* and
Charanjit S. Rihal, MD, FACC*,*
* Division of Cardiovascular Diseases
Division of Biostatistics, Mayo Clinic, Rochester, Minnesota.
Manuscript received January 8, 2007;
revised manuscript received March 12, 2007,
accepted March 19, 2007.
* Reprint requests and correspondence: Dr. Charanjit S. Rihal, Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905. (Email: rihal{at}mayo.edu).
Objectives: This study sought to assess the long-term prognosis of patients with apical ballooning syndrome (ABS).
Background: Apical ballooning syndrome is a recently described acute cardiac syndrome of uncertain etiology and prognosis.
Methods: We retrospectively identified 100 unselected patients with a confirmed diagnosis of ABS by angiography. Recurrences of ABS and mortality were recorded.
Results: Over a mean follow-up of 4.4 ± 4.6 years, 31 patients continued to have episodes of chest pain and 10 patients had recurrence of ABS, for a recurrence rate of 11.4% over the first 4 years. Seventeen patients died in 4.7 ± 4.8 years of follow-up. There was no difference in survival or in cardiovascular survival to an age- and gender-matched population.
Conclusions: The recurrence rate for ABS was 11.4% over 4 years after initial presentation. Recurrence of chest pain is common. Four-year survival was not different from that in an age-matched and gender-matched population.
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Abbreviations and Acronyms
| | ABS = apical ballooning syndrome | | ECG = electrocardiographic/electrocardiography |
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