Advertisement

Click here for more guidelines.
2012 ACCF/ AATS/ SCAI/ STS Expert Consensus Document on Transcatheter Aortic Valve Replacement
ACCF/ SCAI/ STS/ AATS/ AHA/ ASNC/ HFSA/ SCCT 2012 Appropriate Use Criteria for Coronary Revascularization Focused Update
2012 ACCF/ AHA/ ACR/ SCAI/ SIR/ STS/ SVM/ SVN Key Data Elements and Definitions for Peripheral Atherosclerotic Vascular Disease

 
About JACC CME
Policy on Privacy and Confidentiality
Disclosures
Important Information
 

JACC Imaging Homepage JACC Interventions Homepage
Still not a subscriber to JACC Imaging or JACC Interventions?
Click here
to sign up now!

Submit Manuscripts
Author Information
Subscribe/Renew
Order Reprints
Email Alerts
Feedback
RSS Feed
CME
 
 

Cardiosmart
Cardiosource
CVN
Imaging Library
JACC Imaging
JACC Interventions
 
 

About the Journal
Editorial Board & Staff
 
CME Topic Collections Past Issues Search Current Issue Home
     

J Am Coll Cardiol, 2007; 49:2191-2201, doi:10.1016/j.jacc.2007.02.043 (Published online 17 May 2007).
© 2007 by the American College of Cardiology Foundation
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow View Supplemental Tables and Figures
Right arrow All Versions of this Article:
j.jacc.2007.02.043v1
49/22/2191    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (51)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mihaljevic, T.
Right arrow Articles by Lytle, B. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mihaljevic, T.
Right arrow Articles by Lytle, B. W.
Related Collections
Right arrowRelated Articles

CLINICAL RESEARCH: CARDIAC SURGERY

Impact of Mitral Valve Annuloplasty Combined With Revascularization in Patients With Functional Ischemic Mitral Regurgitation

Tomislav Mihaljevic, MD*,*, Buu-Khanh Lam, MD*, Jeevanantham Rajeswaran, MSc{dagger}, Masami Takagaki, MD*, Michael S. Lauer, MD{ddagger}, A. Marc Gillinov, MD*,a, Eugene H. Blackstone, MD*,{dagger} and Bruce W. Lytle, MD*

* Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio
{dagger} Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio
{ddagger} Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio.

Manuscript received September 8, 2006; revised manuscript received February 5, 2007, accepted February 5, 2007.

* Reprint requests and correspondence: Dr. Tomislav Mihaljevic, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, 9500 Euclid Avenue, Desk F24, Cleveland, Ohio 44195. (Email: mihaljt{at}ccf.org).

This paper was presented at the 55th Annual Meeting of the American College of Cardiology, Atlanta, Georgia, March 11 to 14, 2006.

Objectives: The aim of this work was to determine whether mitral valve (MV) annuloplasty benefits patients with moderate/severe (3+/4+) functional ischemic mitral regurgitation (MR) who undergo coronary artery bypass grafting (CABG).

Background: Mitral regurgitation is a strong predictor of poor outcomes in patients with ischemic cardiomyopathy; whether correcting it at the time of CABG improves outcomes is less certain.

Methods: From 1991 to 2003, 390 patients with 3+/4+ ischemic MR had CABG with (n = 290) or without (n = 100) MV annuloplasty. Groups were propensity-matched using demographics, extent of coronary disease, regional wall motion, and quantitative electrocardiography. Survival, echocardiographic severity of MR, and New York Heart Association (NYHA) functional class were compared.

Results: One-, 5-, and 10-year survival was 88%, 75%, and 47% after CABG alone and 92%, 74%, and 39% after CABG + MV annuloplasty (p = 0.6). Mortality was increased in patients with severe lateral wall motion abnormalities (p = 0.05), ST-segment elevation in lateral leads (p < 0.004), and higher QRS voltage sum (p < 0.0001). Patients undergoing CABG alone were more likely to have 3+/4+ postoperative MR than those undergoing CABG + MV annuloplasty (48% vs. 12% at 1 year, p < 0.0001). The NYHA functional class substantially improved in both groups (p < 0.001) and remained improved; at 5 years, 23% of patients having CABG + mitral annuloplasty and 25% having CABG alone were in NYHA functional class III/IV.

Conclusions: Although CABG + MV annuloplasty reduces postoperative MR and improves early symptoms compared with CABG alone, it does not improve long-term functional status or survival in patients with severe functional ischemic MR. The MV annuloplasty in this setting, without addressing fundamental ventricular pathology, is insufficient to improve long-term clinical outcomes.

Abbreviations and Acronyms
  CABG = coronary artery bypass grafting
  CL = confidence limits
  IRB = institutional review board
  LV = left ventricular
  MR = mitral regurgitation
  MRI = magnetic resonance imaging
  MV = mitral valve
  NYHA = New York Heart Association
  PET = positron emission tomography
  TEE = transesophageal echocardiogram
  TTE = transthoracic echocardiogram


Related Articles

Inside This Issue of JACC
J. Am. Coll. Cardiol. 2007 49: A37-A38. [Full Text] [PDF]

Adding Mitral Valve Annuloplasty to Surgical Revascularization Does Not Benefit Patients With Functional Ischemic Mitral Regurgitation
Robert H. Jones
J. Am. Coll. Cardiol. 2007 49: 2202-2203. [Full Text] [PDF]



This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
P. L. Whitlow, T. Feldman, W. R. Pedersen, D. S. Lim, R. Kipperman, R. Smalling, T. Bajwa, H. C. Herrmann, J. Lasala, J. T. Maddux, et al.
Acute and 12-Month Results With Catheter-Based Mitral Valve Leaflet Repair The EVEREST II (Endovascular Valve Edge-to-Edge Repair) High Risk Study.
J. Am. Coll. Cardiol., January 10, 2012; 59(2): 130 - 139.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
B. J. L. Van den Branden, M. J. Swaans, M. C. Post, B. J. W. M. Rensing, F. D. Eefting, W. Jaarsma, and J. A. S. Van der Heyden
Percutaneous Edge-to-Edge Mitral Valve Repair in High-Surgical-Risk Patients: Do We Hit the Target?
J. Am. Coll. Cardiol. Intv., January 1, 2012; 5(1): 105 - 111.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc ImagingHome page
D. Verhaert, Z. B. Popovic, S. De, C. Puntawangkoon, K. Wolski, B. L. Wilkoff, R. C. Starling, W. H. W. Tang, J. D. Thomas, B. P. Griffin, et al.
Impact of Mitral Regurgitation on Reverse Remodeling and Outcome in Patients Undergoing Cardiac Resynchronization Therapy
Circ Cardiovasc Imaging, January 1, 2012; 5(1): 21 - 26.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc ImagingHome page
E. Angeloni, G. Melina, P. Pibarot, U. Benedetto, S. Refice, G. M. Ciavarella, A. Roscitano, R. Sinatra, and J. R. Pepper
Impact of Prosthesis-Patient Mismatch on the Regression of Secondary Mitral Regurgitation After Isolated Aortic Valve Replacement With a Bioprosthetic Valve in Patients With Severe Aortic Stenosis
Circ Cardiovasc Imaging, January 1, 2012; 5(1): 36 - 42.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
J. D. Robb, M. Minakawa, K. J. Koomalsingh, T. Shuto, A. S. Jassar, S. J. Ratcliffe, R. C. Gorman, and J. H. Gorman III
Posterior leaflet augmentation improves leaflet tethering in repair of ischemic mitral regurgitation,
Eur J Cardiothorac Surg, December 1, 2011; 40(6): 1501 - 1507.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. Auricchio, W. Schillinger, S. Meyer, F. Maisano, R. Hoffmann, G. P. Ussia, G. B. Pedrazzini, J. van der Heyden, S. Fratini, C. Klersy, et al.
Correction of Mitral Regurgitation in Nonresponders to Cardiac Resynchronization Therapy by MitraClip Improves Symptoms and Promotes Reverse Remodeling.
J. Am. Coll. Cardiol., November 15, 2011; 58(21): 2183 - 2189.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
D.-H. Kang, B. J. Sun, D.-H. Kim, S.-C. Yun, J.-M. Song, S. J. Choo, C. H. Chung, J.-K. Song, J.-W. Lee, S.-W. Park, et al.
Percutaneous Versus Surgical Revascularization in Patients With Ischemic Mitral Regurgitation
Circulation, September 13, 2011; 124(11_suppl_1): S156 - S162.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. A. Acker, M. Jessup, S. F. Bolling, J. Oh, R. C. Starling, D. L. Mann, H. N. Sabbah, R. Shemin, J. Kirklin, and S. H. Kubo
Mitral valve repair in heart failure: Five-year follow-up from the mitral valve replacement stratum of the Acorn randomized trial
J. Thorac. Cardiovasc. Surg., September 1, 2011; 142(3): 569 - 574.e1.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. M. Calafiore, A. L. Iaco, A. Bivona, E. Varone, S. Scandura, P. Greco, A. Romeo, and M. Di Mauro
Echocardiographically based treatment of chronic ischemic mitral regurgitation
J. Thorac. Cardiovasc. Surg., May 1, 2011; 141(5): 1150 - 1156.e1.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Heart FailHome page
O. Franzen, J. van der Heyden, S. Baldus, M. Schluter, W. Schillinger, C. Butter, R. Hoffmann, R. Corti, G. Pedrazzini, M. J. Swaans, et al.
MitraClip(R) therapy in patients with end-stage systolic heart failure
Eur J Heart Fail, May 1, 2011; 13(5): 569 - 576.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
V. Dor, F. Civaia, C. Alexandrescu, M. Sabatier, and F. Montiglio
Favorable effects of left ventricular reconstruction in patients excluded from the Surgical Treatments for Ischemic Heart Failure (STICH) trial.
J. Thorac. Cardiovasc. Surg., April 1, 2011; 141(4): 905 - 916.e4.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
T. Feldman and M. Cilingiroglu
Percutaneous Leaflet Repair and Annuloplasty for Mitral Regurgitation
J. Am. Coll. Cardiol., February 1, 2011; 57(5): 529 - 537.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol IntvHome page
J. Harnek, J. G. Webb, K.-H. Kuck, C. Tschope, A. Vahanian, C. E. Buller, S. K. James, C. P. Tiefenbacher, and G. W. Stone
Transcatheter Implantation of the MONARC Coronary Sinus Device for Mitral Regurgitation: 1-Year Results From the EVOLUTION Phase I Study (Clinical Evaluation of the Edwards Lifesciences Percutaneous Mitral Annuloplasty System for The Treatment of Mitral Regurgitation)
J. Am. Coll. Cardiol. Intv., January 1, 2011; 4(1): 115 - 122.
[Abstract] [Full Text] [PDF]

Home page
 Oxford Textbook of Heart FailureHome page
G. Ducroq, B. Iung, and A. Vahanian
33 Valvular heart disease
Oxford Textbook of Heart Failure, January 1, 2011; 1(1): med-9780199577729-chapter - med-9780199577729-chapter.
[Abstract] [Full Text]

Home page
 Eur Heart JHome page
L. A. Pierard and B. A. Carabello
Ischaemic mitral regurgitation: pathophysiology, outcomes and the conundrum of treatment
Eur. Heart J., December 2, 2010; 31(24): 2996 - 3005.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. A. ten Brinke, R. J. Klautz, S. A. Tulner, H. F. Verwey, J. J. Bax, V. Delgado, E. R. Holman, M. J. Schalij, E. E. van der Wall, J. Braun, et al.
Clinical and Functional Effects of Restrictive Mitral Annuloplasty at Midterm Follow-Up in Heart Failure Patients
Ann. Thorac. Surg., December 1, 2010; 90(6): 1913 - 1920.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc IntervHome page
J. Solis, R. A. Levine, B. Johnson, J. L. Guerrero, M. D. Handschumacher, S. Sullivan, K. Lam, J. Berlin, G. J. C. Braithwaite, O. K. Muratoglu, et al.
Polymer Injection Therapy to Reverse Remodel the Papillary Muscles: Efficacy in Reducing Mitral Regurgitation in a Chronic Ischemic Model
Circ Cardiovasc Interv, October 1, 2010; 3(5): 499 - 505.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
K. Takeda, K. Taniguchi, Y. Shudo, S. Kainuma, S. Hamada, H. Matsue, G. Matsumiya, and Y. Sawa
Mechanism of Beneficial Effects of Restrictive Mitral Annuloplasty in Patients With Dilated Cardiomyopathy and Functional Mitral Regurgitation
Circulation, September 14, 2010; 122(11_suppl_1): S3 - S9.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. Matsuzaki, M. Morita, H. Hamamoto, M. Noma, J. D. Robb, M. J. Gillespie, J. H. Gorman III, and R. C. Gorman
Elimination of Ischemic Mitral Regurgitation Does Not Alter Long-Term Left Ventricular Remodeling in the Ovine Model
Ann. Thorac. Surg., September 1, 2010; 90(3): 788 - 794.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
G. Lutter, R. Quaden, K. Iino, A. Hagemann, J. Renner, T. Humme, J. Cremer, and L. Lozonschi
Mitral valved stent implantation,
Eur J Cardiothorac Surg, September 1, 2010; 38(3): 350 - 355.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
N. M. Van Mieghem, N. Piazza, R. H. Anderson, A. Tzikas, K. Nieman, L. E. De Laat, J. S. McGhie, M. L. Geleijnse, T. Feldman, P. W. Serruys, et al.
Anatomy of the Mitral Valvular Complex and Its Implications for Transcatheter Interventions for Mitral Regurgitation
J. Am. Coll. Cardiol., August 17, 2010; 56(8): 617 - 626.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. Y. Yoon, N. G. Smedira, E. R. Nowicki, K. J. Hoercher, J. Rajeswaran, E. H. Blackstone, and B. W. Lytle
Decision support in surgical management of ischemic cardiomyopathy
J. Thorac. Cardiovasc. Surg., February 1, 2010; 139(2): 283 - 293.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
T. G. Di Salvo, M. A. Acker, G. W. Dec, and J. G. Byrne
Mitral Valve Surgery in Advanced Heart Failure
J. Am. Coll. Cardiol., January 26, 2010; 55(4): 271 - 282.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
W. Bouma, I. C. C. van der Horst, I. J. Wijdh-den Hamer, M. E. Erasmus, F. Zijlstra, M. A. Mariani, and T. Ebels
Chronic ischaemic mitral regurgitation. Current treatment results and new mechanism-based surgical approaches
Eur J Cardiothorac Surg, January 1, 2010; 37(1): 170 - 185.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
E. Picano, P. Pibarot, P. Lancellotti, J. L. Monin, and R. O. Bonow
The Emerging Role of Exercise Testing and Stress Echocardiography in Valvular Heart Disease
J. Am. Coll. Cardiol., December 8, 2009; 54(24): 2251 - 2260.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. Penicka, H. Linkova, O. Lang, R. Fojt, V. Kocka, M. Vanderheyden, and J. Bartunek
Predictors of Improvement of Unrepaired Moderate Ischemic Mitral Regurgitation in Patients Undergoing Elective Isolated Coronary Artery Bypass Graft Surgery
Circulation, October 13, 2009; 120(15): 1474 - 1481.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
T. Mihaljevic, A. M. Gillinov, and J. F. Sabik III
Functional Ischemic Mitral Regurgitation: Myocardial Viability as a Predictor of Postoperative Outcome After Isolated Coronary Artery Bypass Grafting
Circulation, October 13, 2009; 120(15): 1459 - 1461.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. L. Williams, M. A. Daneshmand, J. G. Jollis, J. R. Horton, L. K. Shaw, M. Swaminathan, R. D. Davis, D. D. Glower, P. K. Smith, and C. A. Milano
Mitral Gradients and Frequency of Recurrence of Mitral Regurgitation After Ring Annuloplasty for Ischemic Mitral Regurgitation
Ann. Thorac. Surg., October 1, 2009; 88(4): 1197 - 1201.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. V. Badiwala, S. Verma, and V. Rao
Surgical Management of Ischemic Mitral Regurgitation
Circulation, September 29, 2009; 120(13): 1287 - 1293.
[Full Text] [PDF]

Home page
 CirculationHome page
F. Langer, T. Kunihara, K. Hell, R. Schramm, K. I. Schmidt, D. Aicher, M. Kindermann, and H.-J. Schafers
RING+STRING: Successful Repair Technique for Ischemic Mitral Regurgitation With Severe Leaflet Tethering
Circulation, September 15, 2009; 120(11_suppl_1): S85 - S91.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J.-H. Kim, O. Kocaturk, C. Ozturk, A. Z. Faranesh, M. Sonmez, S. Sampath, C. E. Saikus, A. H. Kim, V. K. Raman, J. A. Derbyshire, et al.
Mitral Cerclage Annuloplasty, A Novel Transcatheter Treatment for Secondary Mitral Valve Regurgitation: Initial Results in Swine
J. Am. Coll. Cardiol., August 11, 2009; 54(7): 638 - 651.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. Trento, S. Goland, M. A. De Robertis, and L. S.C. Czer
COUNTERPOINT: Efficacy of adding mitral valve restrictive annuloplasty to coronary artery bypass grafting in patients with moderate ischemic mitral valve regurgitation.
J. Thorac. Cardiovasc. Surg., August 1, 2009; 138(2): 286 - 288.
[Full Text] [PDF]

Home page
 Circ Cardiovasc IntervHome page
S. Sack, P. Kahlert, L. Bilodeau, L. A. Pierard, P. Lancellotti, V. Legrand, J. Bartunek, M. Vanderheyden, R. Hoffmann, P. Schauerte, et al.
Percutaneous Transvenous Mitral Annuloplasty: Initial Human Experience With a Novel Coronary Sinus Implant Device
Circ Cardiovasc Interv, August 1, 2009; 2(4): 277 - 284.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
B. de Varennes, R. Chaturvedi, S. Sidhu, A. V. Cote, W. L. P. Shan, C. Goyer, R. Hatzakorzian, J. Buithieu, and A. Sniderman
Initial Results of Posterior Leaflet Extension for Severe Type IIIb Ischemic Mitral Regurgitation
Circulation, June 2, 2009; 119(21): 2837 - 2843.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. M. Bolman III
Have We Found the Surgical Solution for Ischemic Mitral Regurgitation?
Circulation, June 2, 2009; 119(21): 2755 - 2757.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. Silberman, M. W. Klutstein, T. Sabag, A. Oren, D. Fink, O. Merin, and D. Bitran
Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings
Ann. Thorac. Surg., June 1, 2009; 87(6): 1721 - 1727.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
J. Kempfert, J. Blumenstein, M. W. A. Chu, P. Pritzwald-Stegmann, T. Kobilke, V. Falk, F. W. Mohr, and T. Walther
Minimally invasive off-pump valve-in-a-ring implantation: the atrial transcatheter approach for re-operative mitral valve replacement after failed repair
Eur J Cardiothorac Surg, June 1, 2009; 35(6): 965 - 969.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll Cardiol ImgHome page
V. Delgado, L. F. Tops, J. D. Schuijf, A. de Roos, J. Brugada, M. J. Schalij, J. D. Thomas, and J. J. Bax
Assessment of mitral valve anatomy and geometry with multislice computed tomography.
J. Am. Coll. Cardiol. Img., May 1, 2009; 2(5): 556 - 565.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Flynn, R. Curtin, E. R. Nowicki, J. Rajeswaran, S. D. Flamm, E. H. Blackstone, and T. Mihaljevic
Regional wall motion abnormalities and scarring in severe functional ischemic mitral regurgitation: A pilot cardiovascular magnetic resonance imaging study.
J. Thorac. Cardiovasc. Surg., May 1, 2009; 137(5): 1063 - 70.e2.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
M. Di Mauro, A. Bivona, A. L. Iaco, M. Contini, M. Gagliardi, E. Varone, S. Gallina, and A. M. Calafiore
Mitral valve surgery for functional mitral regurgitation: prognostic role of tricuspid regurgitation
Eur J Cardiothorac Surg, April 1, 2009; 35(4): 635 - 640.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. M. Calafiore, S. Gallina, A. L. Iaco, M. Contini, A. Bivona, M. Gagliardi, P. Bosco, and M. Di Mauro
Mitral Valve Surgery for Functional Mitral Regurgitation: Should Moderate-or-More Tricuspid Regurgitation Be Treated? A Propensity Score Analysis
Ann. Thorac. Surg., March 1, 2009; 87(3): 698 - 703.
[Abstract] [Full Text] [PDF]

Home page
 Circ Cardiovasc ImagingHome page
D. B. Ennis, T. C. Nguyen, A. Itoh, W. Bothe, D. H. Liang, N. B. Ingels, and D. C. Miller
Reduced Systolic Torsion in Chronic "Pure" Mitral Regurgitation
Circ Cardiovasc Imaging, March 1, 2009; 2(2): 85 - 92.
[Abstract] [Full Text] [PDF]

Home page
 ESC Textbook of Cardiovascular MedicineHome page
A. Vahanian, B. Iung, L. Pierard, R. Dion, and J. Pepper
CHAPTER 21 Valvular Heart Disease
ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter.
[Abstract] [Full Text] [PDF]

Home page
 Circ Heart FailHome page
M. A. Acker
Mitral Valve Repair in Patients With Advanced Heart Failure and Severe Functional Mitral Insufficiency Reverses Left Ventricular Remodeling and Improves Symptoms
Circ Heart Fail, November 1, 2008; 1(4): 281 - 284.
[Full Text] [PDF]

Home page
 Circ Heart FailHome page
E. C. McGee Jr
Surgery, Mitral Regurgitation, and Heart Failure: The Valves Are All Repairable But the Patients Are Not
Circ Heart Fail, November 1, 2008; 1(4): 285 - 289.
[Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. M. Calafiore, V. Mazzei, A. L. Iaco, M. Contini, A. Bivona, M. Gagliardi, P. Bosco, S. Gallina, and M. Di Mauro
Impact of Ischemic Mitral Regurgitation on Long-Term Outcome of Patients With Ejection Fraction Above 0.30 Undergoing First Isolated Myocardial Revascularization
Ann. Thorac. Surg., August 1, 2008; 86(2): 458 - 465.
[Abstract] [Full Text] [PDF]

Home page
 ANGIOLOGYHome page
A. M. Calafiore, A. L. Iaco, M. Contini, A. Bivona, E. Varone, P. Greco, and S. Scandura
Mitral Valve Repair for Ischemic Mitral Regurgitation
Angiology, August 1, 2008; 59(2_suppl): 89S - 92S.
[Abstract] [PDF]

Home page
 J Am Coll CardiolHome page
B. A. Carabello
The Current Therapy for Mitral Regurgitation
J. Am. Coll. Cardiol., July 29, 2008; 52(5): 319 - 326.
[Abstract] [Full Text] [PDF]

Home page
 Interact CardioVasc Thorac SurgHome page
K.-u. Fumimoto, T. Fukui, T. Shimokawa, and S. Takanashi
Papillary muscle realignment and mitral annuloplasty in patients with severe ischemic mitral regurgitation and dilated heart
Interact CardioVasc Thorac Surg, June 1, 2008; 7(3): 368 - 371.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. D. Crabtree, M. S. Bailey, M. R. Moon, N. Munfakh, M. K. Pasque, J. S. Lawton, N. Moazami, K. A. Aubuchon, A. S. Al-Dadah, and R. J. Damiano Jr
Recurrent Mitral Regurgitation and Risk Factors for Early and Late Mortality After Mitral Valve Repair for Functional Ischemic Mitral Regurgitation
Ann. Thorac. Surg., May 1, 2008; 85(5): 1537 - 1543.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. H. Jones
The Year in Cardiovascular Surgery
J. Am. Coll. Cardiol., April 29, 2008; 51(17): 1707 - 1718.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
A. N. DeMaria, J. J. Bax, O. Ben-Yehuda, P. Clopton, G. K. Feld, G. S. Ginsburg, B. H. Greenberg, J. D. Knoke, W. Y.W. Lew, J. A.C. Lima, et al.
Highlights of the Year in JACC 2007
J. Am. Coll. Cardiol., January 29, 2008; 51(4): 490 - 512.
[Full Text] [PDF]

Home page
 Journal Watch CardiologyHome page
Can Correcting Mitral Regurgitation Improve the Outcome of Surgical Revascularization?
Journal Watch Cardiology, June 27, 2007; 2007(627): 2 - 2.
[Full Text]

Home page
 J Am Coll CardiolHome page
R. H. Jones
Adding Mitral Valve Annuloplasty to Surgical Revascularization Does Not Benefit Patients With Functional Ischemic Mitral Regurgitation
J. Am. Coll. Cardiol., June 5, 2007; 49(22): 2202 - 2203.
[Full Text] [PDF]


 
  CME Topic Collections Past Issues Search Current Issue Home

Advertisement