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STATE-OF-THE-ART PAPER

Valvular Heart Disease and Pregnancy

Part I: Native Valves

Heart Failure Program, Division of Cardiovascular Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California

Manuscript received January 28, 2005; accepted February 8, 2005.

^_* Reprint requests and correspondence: Dr. Uri Elkayam, Heart Failure Program, Keck School of Medicine, Los Angeles County/University of Southern California Medical Center, Room 7621, 1200 North State Street, Los Angeles, California 90033 (Email: elkayam{at}usc.edu).

Pregnancy in patients with valvular heart disease (VHD) continues to pose a challenge to both physicians and their patients and could be associated with an unfavorable maternal as well as fetal outcome. The purpose of this paper is to review the available clinical data and provide recommendations for the management of patients with VHD during gestation.

Abbreviations and Acronyms   ACE = angiotensin-converting enzyme   AR = aortic regurgitation   AS = aortic stenosis   IM = intramuscular   IV = intravenous   MR = mitral regurgitation   MS = mitral stenosis   MVA = mitral valve area   NYHA = New York Heart Association   PMBV = percutaneous mitral balloon valvuloplasty   PS = pulmonic stenosis

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