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J Am Coll Cardiol, 2005; 46:1921-1930, doi:10.1016/j.jacc.2005.07.042 (Published online 20 October 2005).
© 2005 by the American College of Cardiology Foundation
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CLINICAL RESEARCH: CARDIAC RHYTHM DISORDER

Atrial Tachycardia Arising From the Coronary Sinus Musculature

Electrophysiological Characteristics and Long-Term Outcomes of Radiofrequency Ablation

Nitish Badhwar, MBBS, FACC*, Jonathan M. Kalman, MBBS, PhD, FACC{dagger}, Paul B. Sparks, MBBS, PhD{dagger}, Peter M. Kistler, MBBS{dagger}, Mehran Attari, MD{ddagger}, Marcie Berger, MD, FACC{ddagger}, Randall J. Lee, MD, PhD, FACC*, Jasbir Sra, MD, FACC{ddagger} and Melvin M. Scheinman, MD, FACC*,*

* University of California, San Francisco, San Francisco, California
{dagger} Royal Melbourne Hospital, Melbourne, Australia
{ddagger} Aurora Sinai/St. Luke’s Medical Centers, University of Wisconsin Medical School-MCC, Milwaukee, Wisconsin

Manuscript received April 19, 2005; revised manuscript received May 26, 2005, accepted July 4, 2005.

* Reprint requests and correspondence: Dr. Melvin M. Scheinman, Section of Cardiac Electrophysiology, University of California, San Francisco, 500 Parnassus Avenue, MU-East 434, Box 1354, San Francisco, California 94143. (Email: scheinman{at}medicine.ucsf.edu).

OBJECTIVES: We sought to describe the electrophysiological features and long-term outcome after radiofrequency catheter ablation (RFCA) of atrial tachycardia (AT) arising from the coronary sinus (CS) musculature.

BACKGROUND: Atrial tachycardia requiring RFCA deep within the CS has been described in isolated case reports. However, the mechanism and exact site of origin of this tachycardia have not been well elucidated.

METHODS: The study included 8 patients (5 men) of a consecutive series of 283 patients undergoing RFCA for focal AT.

RESULTS: In sinus rhythm, a discrete potential (P) was noted after the CS atrial electrogram and during tachycardia, the CS (P) preceded the surface P-wave by 30 to 50 ms. The CS (P) always preceded the earliest electrogram in the left atrium (LA). Three-dimensional electroanatomical mapping was available in four patients, and in one case it showed earliest activation in the CS with rapid spread to the proximal CS and then to the LA. Ablation of the AT initially attempted from the earliest site in the LA in three patients was unsuccessful. In all patients the tachycardia was safely and successfully ablated at a site 3.6 cm within the CS. There has been no recurrence over a follow-up of 37 ± 13 months.

CONCLUSIONS: Focal AT emanating deep within the CS musculature can be recognized by a discrete potential associated with the CS atrial signal both during sinus rhythm and tachycardia. Long-term success without complications can be accomplished by ablating within the CS in close proximity to the CS (P).

Abbreviations and Acronyms
  AOD = atrial overdrive pacing
  AT = atrial tachycardia
  CS = coronary sinus
  CS (A) = coronary sinus atrial electrogram
  CS (P) = coronary sinus potential
  LA = left atrium
  LOM = ligament of Marshall
  RA = right atrium
  RFCA = radiofrequency catheter ablation
  3D = three-dimensional




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