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Figure 1 Assessment of Small Intestinal Paracellular Permeability and Passive Carrier-Mediated Transport
(A) Urinary lactulose/mannitol-index in chronic heart failure (CHF) patients (n = 21) and control subjects (n = 20). Assessments were made from 5-h urine collection after ingestion of the test sugar drink. The results reflect increased small intestinal permeability of the gut mucosa in CHF patients compared with control subjects. (B) Urinary recovery of orally administered D-xylose in CHF patients (n = 22) compared with control subjects (n = 21). Assessments were made from 5-h urine collection after ingestion of the test sugar drink. The results reflect reduced activity of carrier-mediated transport of D-xylose.
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