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Figure 3 Effect of VEGF on Infarct Scar Size
(A and B) Hearts injected with MDSC-LacZ and MDSC-VEGF25 cells displayed smaller infarct sizes and scar tissue ratio compared with hearts injected with PBS or MDSC-FLT cells at all time points (*p < 0.05 vs. PBS; p < 0.05 vs. MDSC-FLT). Although hearts injected with MDSC-VEGF50 cells had smaller scars at 2 and 6 weeks, they demonstrated larger infarct sizes and scar tissue ratio at 12 weeks ( p < 0.05 vs. MDSC-VEGF50 12 weeks; #p < 0.05, 2 vs. 12 weeks). LV = left ventricle; other abbreviations as in Figure 1.
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