Table 3 Cardiovascular Magnetic Resonance Ventricular Function and Creatine Kinase Levels in Muscular Dystrophy With and Without Myocardial Fibrosis
|
All (n = 10) |
With MF (n = 7) |
Without MF (n = 3) |
p Value |
|
| LV EF (%) |
53.7 ± 12.5 |
48.3 ± 11.0 |
66.1 ± 0.6 |
0.02 |
| LV EDV (ml/m2) |
68.1 ± 17.6 |
73.7 ± 16.4 |
55.1 ± 14.6 |
0.13 |
| LV ESV (ml/m2) |
32.6 ± 14.8 |
38.5 ± 13.5 |
18.7 ± 5.4 |
0.04 |
| LV mass (g/m2) |
106.8 ± 34.6 |
116.9 ± 36.9 |
83.3 ± 11.9 |
0.17 |
| LV EDD (cm) |
4.7 ± 0.7 |
4.8 ± 0.7 |
4.3 ± 0.3 |
0.28 |
| LV ESD (cm) |
3.4 ± 0.8 |
3.6 ± 0.9 |
3.0 ± 0.2 |
0.23 |
| LV ASWT (mm) |
8.6 ± 0.7 |
8.6 ± 0.5 |
8.7 ± 1.2 |
0.86 |
| LV ILWT (mm) |
8.5 ± 1.1 |
8.6 ± 1.3 |
8.3 ± 0.6 |
0.77 |
| RV EF (%) |
54.8 ± 10.3 |
51.8 ± 9.3 |
61.7 ± 10.9 |
0.18 |
| RV EDV (ml/m2) |
59.0 ± 14.2 |
58.7 ± 11.6 |
59.7 ± 22.4 |
0.93 |
| RV ESV (ml/m2) |
26.6 ± 9.0 |
28.6 ± 9.5 |
21.8 ± 6.5 |
0.30 |
| Total creatine kinase* |
7,278.3 ± 5,644.6 |
5,316.7 ± 3,601.6 |
11,855.3 ± 7,718.3 |
0.09 |
|
| * Normal levels <190 UI/l for men and <225 UI/l for children <12 years old. |
|
ASWT = anteroseptal wall thickness; EDD = end-diastolic diameter; EDV = end-diastolic volume; EF = ejection fraction; ESD = end-systolic diameter; ESV = end-systolic volume; ILWT = inferolateral wall thickness; LV = left ventricular; MF = myocardial fibrosis; RV = right ventricular.
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