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Figure 5 Ex vivo immunohistochemical staining of microvessels. Pink color indicates presence of smooth muscle actin (small vessels indicated by arrows). Shown are microscopic images of samples from a myocardial area injected with adenovirus carrying HSV1-sr39tk only (Adsr39tk) (A), and of another area of the same animal injected with adenovirus carrying HSV1-sr39tk reporter gene together with the VEGF121 gene (AdTk-VEGF) (B). Higher microvascular density is present in the VEGF-exposed area.
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