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Figure 6 Plot of peak circumferential strain (peak Ecc) over time comparing mesenchymal stem cell (MSC)-treated and non-treated animals for 3 myocardial layers (endocardial, epicardial, mid-wall layers). Peak negative Ecc values represent myocardial shortening, whereas increasingly positive values reflect relative myocardial dysfunction. As can be appreciated, peak negative Ecc values at the endocardial and mid-wall layers for MSC-treated infarct regions decrease (i.e., improve) over the 8-week follow-up period compared with the control group, which remained dysfunctional.  p < 0.05 difference within the group;  p < 0.05 difference between groups; n = 6 in each group. MI = myocardial infarction.
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