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Figure 1 CardioSEAL device with STARFlex self-centering composed of an MP35n wire framework and a knitted polyester fabric (A). The fabric scaffold is replaced by a tissue engineered biodegradable porcine intestinal collagen layer (ICL) in the BioSTAR septal repair implant (B). An ionically bound heparin coating is applied to the BioSTAR surface. It retains the same wire framework as the STARFlex device.
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