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Figure 2 Recruitment of isolated endothelial progenitor cells (EPCs) on integrin-binding cyclic Arg-Gly-Asp peptide (cRGD) matrix. (A) After 7 days in culture, adherent cells were counted in multiple microscopic fields. Coating with cRGD (1 µg/ml or 100 µg/ml) resulted in a significant increase in EPC outgrowth compared with uncoated control experiments. The fibronectin coating served as a positive control condition (n = 4, *p < 0.05). (B) Coating with cRGD (1 µg/ml or 100 µg/ml) resulted in a significant increase in EPC arrest under flow conditions compared with uncoated control experiments. The fibronectin coating served as a positive control condition (n = 4, *p < 0.05). FN = fibronectin.
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