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Figure 4 (A through D) Pedigrees are shown. Circles represent female subjects and squares represent male subjects. The arrowhead indicates the proband. Diagonal bars indicate deceased family members. Members carrying the mutation are represented by solid circles or solid squares. Further explanation is given in the figure. AVB = atrioventricular block; BS = Brugada syndrome; PM = patients with a pacemaker; SSS = sick sinus syndrome.





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