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Figure 1 (A) En face inspection of left coronary artery (LCA) and the specific vascular site of flow measurement as indicated by the arrowhead. (B) A color Doppler echocardiography image corresponding to image (A), showing LCA and the flow velocity measurement site, as indicated by an arrowhead. Typical ultrasound biomicroscope images of the proximal LCA in (C) relatively non-diseased and (D) severely atherosclerotic low-density lipoprotein receptor (LDLR)–/– mice. Small arrowheads show the measurement site of lumen diameter. Scale bar = 2 mm in panel A and 1 mm in panels C and D. AO = aorta; LA = left atrium; LV = left ventricle; PA = pulmonary artery.





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