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Figure 3 (Top) Biphasic response of isovolumic relaxation time (IVRT) and E-wave deceleration time (EDT) to stress in patients with restrictive filling at rest; IVRT and EDT both shortened with stress in all patients in group EE, whereas IVRT and EDT both lengthened with stress in all patients in group EA. (Bottom) Relationship between inotropic response and stress-induced changes in tricuspid regurgitation (TR) pressure drop; TR pressure drop decreased with stress in the majority of patients in group EA, and inotropic response (peak aortic acceleration time) was maintained, whereas TR pressure drop increased with stress in the majority of patients in group EE and the inotropic response was impaired. Group EA = restrictive filling at rest, non-restrictive at peak stress; group EE = restrictive filling at rest, remained restrictive at peak stress; PMEA = peak mitral E-wave acceleration rate.
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