CORRESPONDENCE: LETTER TO THE EDITOR
Cardiac Resynchronization in Mildly Symptomatic Heart Failure and Asymptomatic Patients
Sumer K. Dhir, MD*
* Boca Raton Community Hospital, 9284 Ketay Circle, Boca Raton, Florida 33428-1516 (Email: sumerdhir{at}yahoo.com).
I read with interest the results of the REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) trial in the paper by Linde et al. (1). The trial concluded that cardiac resynchronization therapy, in combination with optimal medical therapy, reduces the risk of heart failure hospitalization and improves ventricular structure and function in New York Heart Association functional class I and II patients with previous heart failure symptoms. I think that it is worth noting that the studied population was composed of patients having significantly prolonged QRS duration (average 156 ms) as well as quite severe dilated left ventricular end-diastolic dimensions (average 70 mm). Hence, one should be careful when considering these results in the heart failure patients of New York Heart Association functional classes I and II.
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1. Linde C, Abraham WT, Gold MR, et al. REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) Study Group Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms J Am Coll Cardiol 2008;52:1834-1843.[Abstract/Free Full Text]
Related Article
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Randomized Trial of Cardiac Resynchronization in Mildly Symptomatic Heart Failure Patients and in Asymptomatic Patients With Left Ventricular Dysfunction and Previous Heart Failure Symptoms
- Cecilia Linde, William T. Abraham, Michael R. Gold, Martin St. John Sutton, Stefano Ghio, Claude Daubert REVERSE (REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction) Study Group
J. Am. Coll. Cardiol. 2008 52: 1834-1843.
[Abstract]
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