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Figure 5 MT Prevents Ang II–Induced Cardiac 3-NT Formation and PAI-1 Expression
Mice (n  5) were given Ang II at 0.5 mg/kg for 2 weeks, and then the hearts were collected within the 2 weeks during (indicated by 0.5 m) and 1, 3, 6 months after Ang II administration for measuring 3-NT by Western blotting (A), and PAI-1 mRNA (B) and protein expression (C) by real-time polymerase chain reaction and immunohistochemical staining, respectively. *p < 0.05 versus corresponding control. mRNA = messenger ribonucleic acid; PAI-1 = plasminogen activator inhibitor-1; other abbreviations as in Figure 1.
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