Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 Protein Synthesis
Myosin heavy chain (MHC) synthesis rate (Ks) and degradation rate (Kd) are shown for dogs with severe mitral regurgitation (MR) at 2 weeks (2W), 4 weeks (4W), and 3 months (3M) after initiation of the lesion expressed as a percent of the total pool (A) and as mg/day (B). Because left ventricular mass increased by 30% and no increase in Ks could be detected, a decrease in Kd is inferred. Reprinted with permission from Matsuo et al. (8).
|
