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Figure 4 NOX5 Localization in Human CAD at Different Stages of Atherosclerosis
Immunofluorescent localization of NOX5 in human coronary arteries. The NOX5 (red) was studied in control, non-coronary artery disease (CAD) coronary arteries (A), in coronary artery segments from CAD patients showing no atherosclerosis (B,C), in coronary artery segments showing neointimal hyperplasia (D), and in coronary artery segments with severe complex lesions (E). (C) A magnification of (B) showing the presence of NOX5 in endothelium (double staining; arrows). Green staining represents endothelial cell marker CD31 in (A to D) and smooth muscle cell alpha actin (E). Micrographs show representative staining of at least 5 independent experiments. Abbreviations as in Figure 1.
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