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Figure 3 Cardiomyocyte–Fibroblast Crosstalk
Autocrine and paracrine mechanisms act to amplify humoral and mechanical stimuli resulting in tissue fibrosis. Figure illustration by Rob Flewell. Ang II = angiotensin II; AT-R = angiotensin receptor; ECM = extracellular matrix; TGF = transforming growth factor; TGFβ-R = trasforming growth factor beta receptor.
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