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Figure 1 Immunohistochemical Characterization of Cell Adhesion Complex Proteins in the Infarct Area
Representative microphotographs of immunostaining for β-catenin (A to C),  -catenin (D to F), N-cadherin (G to I), and  E-catenin (J to L) in the infarct area of ruptured hearts (A, D, G, J), and early (B, E, H, K) and late (C, F, I, L) control infarcts. A similar staining intensity for β-catenin, -catenin, and N-cadherin was observed in the intercalated disk regions of the cardiomyocytes in infarct rupture and the 2 control myocardial infarction (MI) groups. E-catenin staining was undetectable in the infarct area of infarct rupture patients (J). However, staining was observed in the early control infarcts (K) as also in the border zone (bz) of late control MIs (L). (M to O) Shows hematoxylin and eosin staining of the infarct area of ruptured patients (M), characterized by the necrotic cardiomyocytes and the massive influx of inflammatory cells. Hematoxylin and eosin staining of an early control MI (N) and the border zone of a late control MI (O) are also shown.
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