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Figure 2 Effects of Sirolimus on Vascular Superoxide Levels
Effects of sirolimus (Sir) exposure on vascular superoxide levels as compared to control animals (Ctr). Aortic cross-sections with DHE labeling (1 µM), which produces red fluorescence when oxidized to ethidium by superoxide. Elastic laminae in media (m) with green autofluorescence. Data are representative of n = 3 independent experiments. a = adventitia; DHE = dihydroethidine; e = endothelium; L-NAME = NG-nitro-L-argine methyl ester.
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