Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 3 Immunohistochemistry
Representative immunohistochemistry of allograft from the nontreated group and the clarithromycin (CAM)-treated group. The sections were incubated with CD4 (a and b), CD8 (c and d), CD11b (e and f), intercellular adhesion molecule (ICAM)-1 (g and h), and nuclear factor- B (NF-B) p65 (i and j). Although CD4+
(a), CD8+
(c), and CD11b+
(e) cells were observed in nontreatment on day 7, CAM treatment markedly attenuated them (b, d, and f). The expression of ICAM-1 (g) and NF-B p65 (i) were observed in nontreatment myocardial infiltrating area; however, CAM treatment markedly attenuated them (h and j). Scale bars = 50 µm (a to j).
|
