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Figure 1 Representative Plot of FMD and Low-FMC
Radial artery diameter changes throughout the study of low–flow-mediated constriction (FMC) and flow-mediated dilation (FMD). After 1 min of resting radial artery diameter measurement, the wrist cuff is inflated (arrowhead) to suprasystolic pressure. At this point, the radial artery diameter progressively decreases in healthy volunteers until it reaches a plateau (low-FMC) at approximately 3' 30" after wrist cuff inflation and does not further constrict for longer occlusion times. Upon wrist cuff deflation (double arrowhead), the increased shear stress causes radial artery dilation (FMD). Therefore, L-FMC is a negative number, while FMD is a positive one. Doppler blood flows are reported at each time point. Image from the analysis software (4).
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