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Figure 4 Histological Characterization of Atherosclerotic Lesions in ApoE–/– Mice
Representative atherosclerotic lesions from ApoE–/– mice treated with high-cholesterol WTD or NC supplemented with PSE, EZE, and their combination (PSE + EZE) stained for (A) oil red O (ORO), (B) collagen (picrosirius red), (C) macrophages (MAC, MOMO-2), and (D) vascular smooth muscle cells (SMC alpha-actin). (E) Semiquantitative grading of stainings: (+) weak staining, (++) moderate staining, (+++) intense staining. I = intima; L = lumen; M = media; other abbreviations as in Figures 1 and 2.
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