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Figure 2 Effects of Plant Sterols on Plasma Cholesterol, Sitosterol, and Campesterol in ApoE–/– Mice
Effect of 6-month treatment of apolipoprotein E (ApoE)–/– mice with a high-cholesterol Western-type diet (WTD) or NC supplemented with PSE, ezetimibe (EZE), and their combination (PSE + EZE) on plasma cholesterol, sitosterol, and campesterol concentrations determined by gas liquid chromatography-mass spectrometry. Values are mean ± SEM (n = 10/group). (A) #p < 0.05 for WTD versus WTD + PSE, WTD + EZE, and WTD + PSE + EZE.  p < 0.05 for WTD + EZE versus WTD + PSE + EZE. *p < 0.05 for WTD + PSE versus WTD, WTD + EZE, and WTD + PSE + EZE. (B) #p < 0.05 for NC versus NC + PSE, NC + EZE, and NC + PSE + EZE. *p < 0.05 for NC, NC + PSE versus NC + EZE, and NC + PSE + EZE. Abbreviations as in Figure 1.
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