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Figure 6 Apoptosis
Rates of LV apoptosis (TUNEL staining) were increased in both border and remote zones compared with the normal rate in murine LV of 50 TUNEL-positive nuclei per 100,000 cells (1). Activation of ACVI expression reduced the rate of apoptosis by about 50% in both regions. Numbers in bars = animals studied; bars = mean values; error bars = 1 SE; p value = probability value for gene effect (2-way analysis of variance). TUNEL = terminal 2'-deoxyuridine 5'-triphosphate nick-end labeling; other abbreviations as in Figure 2.
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