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Figure 4


Figure 4 Absolute Values and Percent Changes Evaluated by MRI

Absolute values (A and C) and percent change (B and D) of total atheroma volume evaluated by MRI in rabbits treated five times with vehicle (control) or different doses of ETC-216. Data are expressed as mean ± SEM. (A and C) Open bars represent pre-treatment; solid bars represent post-treatment. *p < 0.05 versus control post-treatment; ^p < 0.05 versus ETC-216 at 5 mg/kg. (B and D) §p < 0.05 versus control; ¶p < 0.05 versus ETC-216 at 5 mg/kg. MRI = magnetic resonance imaging; other abbreviations as in Figure 1.





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