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Figure 2 Measured Time Course of LV Dyssynchrony and its Recovery in an Animal Model of Dilated HF and a LBBB
Dyssynchrony is assessed using 3-dimensional circumferential strains, calculating a vector sum index that not only provides information about the dispersion of strain values during the heart beat but further amplifies this if they are geographically clustered (i.e., the whole lateral wall is late) (45). Dyssynchrony gradually rises to end-systole and then declines, so dyssynchrony during systole and diastole would be observed. Biventricular pacing (cardiac resynchronization therapy) reduces dyssynchrony during both periods. HF = heart failure; LBBB = left bundle branch block; LV = left ventricular.
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