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Figure 6 In Vivo CD31Rg Expression Increases Circulating Tregs
(Top) The percentage of CD25+/FoxP3+ regulatory T cells (Tregs) within total CD4+ T lymphocytes was significantly increased in the peripheral blood of CD31Rg-treated mice as compared with the controls. *p < 0.01, n = 14 mice/group. (Bottom) The suppressive capacity of Tregs was not altered by CD31Rg treatment (n = 14 mice/group, NS). CD4+CD25 negative T-cells were incubated with Tregs at the indicated ratios, and proliferation was measured as before. Other abbreviations as in Figure 1.
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