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Figure 5 Gene Expression and Activity of Antioxidant Enzymes
(A) Both MnSOD and GPX mRNA levels are increased in MIC compared with NF hearts. Expression of both genes is slightly reduced in DCM and IHD hearts. *p < 0.01 versus NF;  p < 0.05 versus NF. Orange = MnSOD; green = GPX. (B) MnSOD activity didn’t show any changes in MIC, DCM, and IHD compared with control samples. (C) A significant reduction of GPX activity was observed in IHD hearts. *p < 0.01 versus NF. GPX = glutathione peroxidise; MnSOD = manganese superoxide dismutase; other abbreviations as in Figure 2.
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