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Figure 3 Expression of Glucose Transporters (GLUT1 and GLUT4) and Uncoupling Proteins (UCP2 and UCP3)
(A) GLUT1 (orange) and GLUT4 (green) were up-regulated in mitochondrial cardiomyopathy (MIC) compared with NF hearts; GLUT1 was markedly reduced in DCM and slightly reduced in IHD compared with controls; GLUT4 shows a slight reduction in DCM and IHD. *p < 0.001 versus NF. (B) UCP2 (orange) and UCP3 (green) were up-regulated in MIC compared with NF hearts. Both isoforms were down-regulated in DCM and IHD failing hearts, UCP2 showing the lowest amount. *p < 0.001 versus NF. Abbreviations as in Figure 2.
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