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Figure 2 Mechanisms of Therapeutic Interventions on Adiponectin, Insulin Resistance, and Endothelial Function
Lifestyle modifications and cardiovascular drugs such as fenofibrate, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II type I receptor blockers (ARBs), and thiazolidinediones (TZDs) increase plasma levels of adiponectin, reduce insulin resistance, and improve endothelial function. These may be one mechanism to reduce cardiovascular diseases by these therapeutic interventions used in recent clinical trials.
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