Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 8 Activated Caspase-3 Immunohistochemistry of Myocardial Specimens
Activated caspase-3 was present in the cytoplasm of cells with morphology consistent with apoptosis. Positive staining is seen in myocardium of animals treated with doxorubicin (C and D). No staining is seen in control animals fed (A) regular chow or (B) iron-rich chow. Iron-rich chow fed animals treated with doxorubicin (D) show a greater area of staining involving higher number of myocytes compared with regular chow fed animals treated with doxorubicin (C).
|
