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Figure 3 Pharmacokinetics and Pharmacodynamics
(A) Increasing doses of recombinant nematode anticoagulant protein c2 (rNAPc2) were associated with increased plasma drug concentrations at 2 to 6 and 48 h. (B) rNAPc2 increased the international normalized ratio (INR) in a dose-related fashion at 2 to 6 and 48 h.
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