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Figure 3 Intraplaque Hemorrhage
Plaque neovessels are of relatively large caliber and poorly invested with smooth muscle cells, a structural weakness that may be further compromised by matrix degrading enzymes released by inflammatory cells. Intraplaque hemorrhage from these vessels may contribute to plaque instability and/or lesion expansion. MMPs = matrix metalloproteinases. Copyrighted and used with permission of Mayo Foundation for Medical Education and Research.
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