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Figure 1 Summary of LQTS-Associated Channel Mutations in SUD
The putative sudden unexplained death (SUD)–associated pathogenic mutations (yellow circles) identified in this study are depicted with their approximate location on this schematic representation of the linear topology (not drawn to scale) of the cardiac channel subunits implicated in long QT syndrome (LQTS). Numbers shown within the circles correspond to the case numbers in Table 2. Note that the locations of the KCNQ1 and KCNE1 polymorphisms are not shown for case 11. *Functional polymorphism.
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