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Figure 4 Endothelial Cells Proliferate After eNOS S1177D Transfection In Vivo
Histochemical evaluation proliferation (Ki67 positivity) in control (A) and ischemic (B) tissue. Red bar = 50 µm. (C) Quantitative analysis revealed an increased proliferation in eNOS S1177D transfected tissue (3 experiments/group with 5 tissue specimens/condition each). Cx = circumflex coronary artery. (D) Fluorescence microscopy of Ki67 (left), endothelial marker platelet endothelial adhesion molecule-1 (PECAM-1) (middle), and overlay (right), red bar = 10 µm. Abbreviations as in Figure 2.
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