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Figure 5 BNP, cGMP, and Their Ratio in Plasma and Urine in Animals With Normal or Failing Hearts
Bar graphs showing the B-type natriuretic peptide (BNP) concentration (A), plasma cyclic guanosine monophosphate (cGMP) concentration (B), ratio of plasma cGMP to plasma BNP (C), urine cGMP concentration (D), and ratio of urine cGMP to plasma BNP (E) of normal (solid bars) and failing dogs (hatched bars) at baseline and in response to acute administration of BNP, sildenafil (SIL) (B only), and the combination of SIL + BNP. *p  0.03, #p = 0.06: within group comparison to baseline;  p 0.03, ¶p < 0.005: between group (congestive heart failure [CHF] vs. normal) for same intervention;  p 0.04: within group, versus BNP alone.
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