|
|
||||||||||
|
Click on image to view larger version.
Figure 1 Multistage design for genome-wide association study. A multistage design with replication allows testing at a nominal significance threshold with elimination of false-positive associations by replication. Validation in an independent population is essential, with a larger sample size at this step to protect against false-negative associations. SNP = single nucleotide polymorphism.
|
| HOME | SUBSCRIPTIONS | CURRENT ISSUE | PAST ISSUES | CARDIOSOURCE | SEARCH | HELP | FEEDBACK |