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Figure 8 (A)
Representative photomicrographs of hematoxylin-eosin staining of arterial sections 28 days after carotid ligation in mice receiving naloxone (right panel)
or phosphate-buffered saline (PBS) injection (left panel)
. Arrows
indicate borders of the neointima and media. Original magnification 200x. (B)
Morphometric analysis of the lumen, neointima, media, and total vascular areas. Values are mean ± SD of 5 sections in each mouse. *p < 0.05; **p < 0.01; ***p < 0.005 compared with the mice receiving PBS injection. (C)
Degree of neointima formation 28 days after carotid ligation was calculated according to neointima/media area (N/M) ratio. ***p < 0.005 compared with the mice receiving PBS injection (bar
= 100 µm).
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