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Figure 4 Mean within-patient 18
F-fluorodeoxyglucose (FDG) uptake versus inflammation in carotid endarterectomy patients. For each of the 17 subjects, all histologic sections were averaged to generate a mean per-patient value for percentage macrophage staining. Likewise, the corresponding imaging data were combined to generate a mean target-to-background ratio (T/B) for each patient. There was a significant correlation between mean T/B and mean inflammation (r = 0.85; p < 0.001). The correlation remained significant (r = 0.82; p < 0.001) even after the outlier with the highest plaque inflammation was removed from the analysis.
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