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Figure 1 Structural abnormalities in hypertrophic cardiomyopathy (HCM) mutation carriers. (A) Short-axis view of HCM mutation carrier. White arrowhead indicates triangular shaped, blood-containing spot in inferoseptum. Gray cutline represents the image plane of images B through F. (B) Modified 2-chamber view through inferoseptum of healthy volunteer; no crypts can be observed. (C to E) Modified 2-chamber view through inferoseptum of HCM mutation carriers with left ventricular (LV) wall thickness <9 mm; white arrowheads indicate crypts penetrating the myocardium up to the subepicardial layer. (F) Modified 2-chamber view through inferoseptum of HCM mutation carrier with LV wall thickness of 11 mm. The penetration of the crypts can be visualized only up to 70% of the myocardium, as indicated by white arrowheads.
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