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Figure 1


Figure 1 Assessment of morphology and contractile function. (A) Contrast-enhanced multislice computed tomographic (CT) images obtained during positron emission tomography–CT in an animal (animal 5; Table 1) after adenoviral gene transfer (top) and a control animal (animal 10; Table 1) after saline injection (bottom). Surface-rendered images (left, anterior view) allow for accurate identification of clip-marked injection sites in basal anterior and distal anterolateral wall (arrows). Ventricular function is determined from end-diastolic (middle right) and end-systolic short-axis images (right). (B and C) Mean ± SD of regional end-diastolic wall thickness and thickening.





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