Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 Embryonic development of the left ventricular wall in a chick. (A) The tubular myocardium (My) (2 to 3 cell layers thick) is separated from the endocardium (En) by acellular cardiac jelly (CJ). (B) The inner layers proliferate to form trabeculations (Tr), which are nourished by the blood circulating through the intertrabecular spaces (ITS). The outer layers proliferate and undergo compaction (Co) and are covered by epicardium (arrowhead). (C) By the sixth embryonic day, the compact layer has thickened and is invaded by developing coronaries from the epicardial surface. (D) In the neonatal (day 10) heart, the multilayered compact architecture of the left ventricular wall is clearly appreciated with the innermost layer merging with the papillary muscle (mp). On the right side of each picture is a schematic drawing illustrating the major steps in development of ventricular myoarchitecture. Scale bars = A, B, C, 100 µm; D, 500 µm. Reproduced from Sedmera et al. (20) with permission.
|
